EC number

EC 200-663-8 Chloroform

CAS 56-23-5 · CAS 67-66-3 · CAS 71-55-6 · CAS 75-35-4 · CAS 76-01-7 · CAS 79-00-5 · CAS 79-34-5 · CAS 630-20-6 · EC 200-262-8 · EC 200-663-8 · EC 200-756-3 · EC 200-864-0 · EC 200-925-1 · EC 201-166-9 · EC 201-197-8 · Index No 602-006-00-4

Where EC 200-663-8 appears: every table entry that prints it among its identifiers, in the newest version of each act this record holds, and every recorded change to those entries. Many entries name a group of substances and print no number, so absence here is not absence from the law. Not legal advice.

Where it appears now

CLP Annex VI section 3, Index No 602-006-00-4

Last changed in the version detected 13 August 2026 · Annex VI on this site

Annex VI section 3, table 1
Index No	Chemical name	EC No	CAS No	Classification		Labelling			Specific Conc. Limits, M-factors and ATEs	Notes
Index No	Chemical name	EC No	CAS No	Hazard Class and Category Code(s)	Hazard statement Code(s)	Pictogram, Signal Word Code(s)	Hazard statement Code(s)	Suppl. Hazard statement Code(s)	Specific Conc. Limits, M-factors and ATEs	Notes
602-006-00-4	chloroform; trichloromethane	200-663-8	67-66-3	Carc. 2 Repr. 2 Acute Tox. 3 Acute Tox. 4 STOT RE 1 Eye Irrit. 2 Skin Irrit. 2	H351 H361d H331 H302 H372 H319 H315	GHS06 GHS08 Dgr	H351 H361d H331 H302 H372 H319 H315

CLP Annex VI section 3, table 2, Index No 602-006-00-4

Last changed in the version detected 13 August 2026 · Annex VI on this site

Annex VI section 3, table 2
Index No	International Chemical Identification	EC No	CAS No	Classification	Labelling	Concentration Limits	Notes
602-006-00-4	chloroform; trichloromethane	200-663-8	67-66-3	Carc. Cat. 3; R40 Repr. Cat. 3; R63 Xn; R20/22-48/20 Xi; R36/38	Xn R: 20/22-36/38-40-48/20-63 S: (2-)36/37

Cosmetics Regulation Annex II, Reference number 366

No change to this entry since the first version the record holds, in force 11 July 2013. · Annex II on this site

Annex II, table 1
Reference number	Substance identification
Reference number	Chemical name/INN	CAS number	EC number
a	b	c	d
366	Chloroform	67-66-3	200-663-8

PIC Regulation Annex I, the entry for Chloroform

Last changed in the version in force 1 July 2022, by Regulation (EU) 2022/643, the act that change names · Annex I on this site

Annex I, table 1
Chemical	CAS No	EC No	CN code	Subcategory	Use limitation	Countries for which no notification is required
Chloroform	67-66-3	200-663-8	ex29031300	i(2)	b

REACH Annex XVII, Entry 32

Last changed in the version in force 27 June 2009, by Regulation (EC) No 552/2009, the act that change names · Annex XVII on this site

Annex XVII, table 1
Column 1 Designation of the substance, of the group of substances or of the mixture	Column 2 Conditions of restriction
32. Chloroform CAS No 67-66-3 EC No 200-663-8 34. 1,1,2-Trichloroethane CAS No 79-00-5 EC No 201-166-9 35. 1,1,2,2-Tetrachloroethane CAS No 79-34-5 EC No 201-197-8 36. 1,1,1,2-Tetrachloroethane CAS No 630-20-6 37. Pentachloroethane CAS No 76-01-7 EC No 200-925-1 38. 1,1-Dichloroethene CAS No 75-35-4 EC No 200-864-0	Without prejudice to the other parts of this Annex, the following shall apply to entries 32 to 38. 1. Shall not be placed on the market, or used, as substances, as constituents of other substances, or in mixtures in concentrations equal to or greater than 0,1 % by weight, where the substance or mixture is intended for supply to the general public and/or is intended for diffusive applications such as in surface cleaning and cleaning of fabrics. 2. Without prejudice to the application of other Community provisions on the classification, packaging and labelling of substances and mixtures, suppliers shall ensure before the placing on the market that the packaging of such substances and mixtures containing them in concentrations equal to or greater than 0,1 % by weight is visibly, legibly and indelibly marked as follows: For use in industrial installations only. By way of derogation this provision shall not apply to: (a) medicinal or veterinary products as defined by Directive 2001/82/EC and Directive 2001/83/EC; (b) cosmetic products as defined by Directive 76/768/EEC.

Look up a number

Type a CAS or EC number, with or without its hyphens, or an Index No into the search box at the top of the page: it reads 50000 as CAS 50-00-0. Every number is also listed by act on the substances page.

Its history

13 August 2026 · amended · CLP Annex VI section 3, Index No 602-006-00-4

Recorded in the version detected 13 August 2026. The change on its version page

Amended entries, Annex VI section 3, table 1
Identifiers	Version	Index No	International Chemical Identification	EC No	CAS No	Classification		Labelling			Specific Conc. Limits, M-factors
Identifiers	Version	Index No	International Chemical Identification	EC No	CAS No	Hazard Class and Category Code(s)	Hazard statement Code(s)	Pictogram, Signal Word Code(s)	Hazard statement Code(s)	Suppl. Hazard statement Code(s)
Index No 602-006-00-4CAS 67-66-3EC 200-663-8	Before	602-006-00-4	~~trichloromethane; chloroform~~	200-663-8	67-66-3	Carc. 2 ~~Acute Tox. 4 * STOT RE 2 * STOT RE 2 * Skin Irrit. 2~~	H351 ~~H302 H373 H373 H315~~	~~GHS07 GHS08 Wng~~	H351 ~~H302 H373 H373 H315~~		* STOT RE 2; H373: C ≥ 5 %
	After	602-006-00-4	chloroform; trichloromethane	200-663-8	67-66-3	Carc. 2	H351	GHS06	H351
						Repr. 2	H361d	GHS08	H361d
						Acute Tox. 3	H331	Dgr	H331
						Acute Tox. 4	H302		H302
						STOT RE 1	H372		H372
						Eye Irrit. 2	H319		H319
						Skin Irrit. 2	H315		H315

13 August 2026 · amended · CLP Annex VI section 3, table 2, Index No 602-006-00-4

Recorded in the version detected 13 August 2026. The change on its version page

Amended entries, Annex VI section 3, table 2
Identifiers	Version	Index No	International Chemical Identification	EC No	CAS No	Classification	Labelling	Concentration Limits	Notes
Index No 602-006-00-4CAS 67-66-3EC 200-663-8	Before	602-006-00-4	~~trichloromethane; chloroform~~	200-663-8	67-66-3	~~Xn; R22-48/20/22 Xi; R38~~ Carc. Cat. 3; R40	Xn R: ~~22-38-40-48/20/22~~ S: (2-)36/37	~~Xn; R22: C ≥ 5 % Xn; R48/20/22: C ≥ 5 %~~
Index No 602-006-00-4CAS 67-66-3EC 200-663-8	After	602-006-00-4	chloroform; trichloromethane	200-663-8	67-66-3	Carc. Cat. 3; R40Repr. Cat. 3; R63 Xn; R20/22-48/20 Xi; R36/38	Xn R: 20/22-36/38-40-48/20-63 S: (2-)36/37

1 July 2022 · amended · PIC Regulation Annex I, the entry for Chloroform

Recorded in the version in force 1 July 2022, by Regulation (EU) 2022/643, the act that change names. The change on its version page

Amended entries, Annex I, table 1
Identifiers	Version	Chemical	CAS No	EC No	CN code	Subcategory	Use limitation	Countries for which no notification is required
ChloroformCAS 67-66-3EC 200-663-8	Before	Chloroform	67-66-3	200-663-8	~~29031300~~	i(2)	b
ChloroformCAS 67-66-3EC 200-663-8	After	Chloroform	67-66-3	200-663-8	ex29031300	i(2)	b

1 December 2019 · amended · CLP Annex VI section 3, Index No 602-006-00-4

Recorded in the version in force 1 December 2019, by Regulation (EU) 2018/669 and 2 others, the acts that change names. The change on its version page

Amended entries, Annex VI section 3, table 1
Identifiers	Version	Index No	Chemical name	EC No	CAS No	Classification		Labelling			Specific Conc. Limits, M-factors	Notes
Identifiers	Version	Index No	Chemical name	EC No	CAS No	Hazard Class and Category Code(s)	Hazard statement Code(s)	Pictogram, Signal Word Code(s)	Hazard statement Code(s)	Suppl. Hazard statement Code(s)	Specific Conc. Limits, M-factors	Notes
Index No 602-006-00-4CAS 67-66-3EC 200-663-8	Before	602-006-00-4	chloroform; trichloromethane	200-663-8	67-66-3	Carc. 2	H351	GHS06	H351
						~~Repr. 2~~	~~H361d~~	~~GHS08~~	~~H361d~~
						~~Acute Tox. 3~~	~~H331~~	~~Dgr~~	~~H331~~
						~~Acute Tox. 4~~	~~H302~~		~~H302~~
						~~STOT RE 1~~	~~H372~~		~~H372~~
						~~Eye Irrit. 2~~	~~H319~~		~~H319~~
						~~Skin Irrit. 2~~	~~H315~~		~~H315~~
	After	602-006-00-4	chloroform; trichloromethane	200-663-8	67-66-3	Carc. 2Repr. 2 Acute Tox. 3 Acute Tox. 4 STOT RE 1 Eye Irrit. 2 Skin Irrit. 2	H351H361d H331 H302 H372 H319 H315	GHS06GHS08 Dgr	H351H361d H331 H302 H372 H319 H315

27 June 2009 · amended · REACH Annex XVII, Entry 32

Recorded in the version in force 27 June 2009, by Regulation (EC) No 552/2009, the act that change names. The change on its version page

Amended entries, Annex XVII, table 1
Identifiers	Version	Column 1 Designation of the substance, of the group of substances or of the mixture	Column 2 Conditions of restriction
Entry 32CAS 56-23-5CAS 630-20-6CAS 67-66-3CAS 71-55-6CAS 75-35-4CAS 76-01-7CAS 79-00-5CAS 79-34-5EC 200-262-8EC 200-663-8EC 200-756-3EC 200-864-0EC 200-925-1EC 201-166-9EC 201-197-8	Before	32. Chloroform CAS No 67-66-3 ~~EINECS~~ No 200-663-8 ~~33. Carbon tetrachloride-tetrachloromethane CAS No 56-23-5 EINECS No 200-262-8~~ 34. ~~1,1,2 Trichloroethane~~ CAS No 79-00-5 ~~EINECS~~ No 201-166-9 35. ~~1,1,2,2 Tetrachloroethane~~ CAS No 79-34-5 ~~EINECS~~ No 201-197-8 36. ~~1,1,1,2 Tetrachloroethane~~ CAS No 630-20-6 37. Pentachloroethane CAS No 76-01-7 ~~EINECS~~ No 200-925-1 38. ~~1,1 Dichloroethylene~~ CAS No 75-35-4 ~~EINECS~~ No 200-864-0 ~~39. 1,1,1 Trichloroethane, methyl chloroform CAS No 71-55-6 EINECS No 200-756-3~~	1. Shall not be ~~used~~ in concentrations equal to or greater than 0,1 % by ~~weight in substances and mixtures placed on~~ the ~~market~~ for ~~sale~~ to the general public and/or in diffusive applications such as in surface cleaning and cleaning of fabrics. 2. Without prejudice to the application of other Community provisions on the classification, packaging and labelling of ~~dangerous~~ substances and mixtures, the packaging of such substances and mixtures containing them in concentrations equal to or greater than 0,1 % ~~shall be legible~~ and indelibly marked as follows: For use in industrial installations only. By way of derogation this provision shall not apply to: (a) medicinal or veterinary products as defined by Directive 2001/82/EC and Directive 2001/83/EC; (b) cosmetic products as defined by Directive 76/768/EEC.
	After	32. Chloroform CAS No 67-66-3 EC No 200-663-8 34. 1,1,2-Trichloroethane CAS No 79-00-5 EC No 201-166-9 35. 1,1,2,2-Tetrachloroethane CAS No 79-34-5 EC No 201-197-8 36. 1,1,1,2-Tetrachloroethane CAS No 630-20-6 37. Pentachloroethane CAS No 76-01-7 EC No 200-925-1 38. 1,1-Dichloroethene CAS No 75-35-4 EC No 200-864-0	Without prejudice to the other parts of this Annex, the following shall apply to entries 32 to 38. 1. Shall not be placed on the market, or used, as substances, as constituents of other substances, or in mixtures in concentrations equal to or greater than 0,1 % by weight, where the substance or mixture is intended for supply to the general public and/or is intended for diffusive applications such as in surface cleaning and cleaning of fabrics. 2. Without prejudice to the application of other Community provisions on the classification, packaging and labelling of substances and mixtures, suppliers shall ensure before the placing on the market that the packaging of such substances and mixtures containing them in concentrations equal to or greater than 0,1 % by weight is visibly, legibly and indelibly marked as follows: For use in industrial installations only. By way of derogation this provision shall not apply to: (a) medicinal or veterinary products as defined by Directive 2001/82/EC and Directive 2001/83/EC; (b) cosmetic products as defined by Directive 76/768/EEC.

20 January 2009 · amended · REACH Annex XVII, Entry 32

Recorded in the version in force 20 January 2009, by Regulation (EC) No 1272/2008, the act that change names. The change on its version page

Amended entries, Annex XVII, table 1
Identifiers	Version	Designation of the substance, of the groups of substances or of the mixture	Conditions of restriction
Entry 32CAS 56-23-5CAS 630-20-6CAS 67-66-3CAS 71-55-6CAS 75-35-4CAS 76-01-7CAS 79-00-5CAS 79-34-5EC 200-262-8EC 200-663-8EC 200-756-3EC 200-864-0EC 200-925-1EC 201-166-9EC 201-197-8	Before	32. Chloroform CAS No 67-66-3 EINECS No 200-663-8 33. Carbon tetrachloride-tetrachloromethane CAS No 56-23-5 EINECS No 200-262-8 34. 1,1,2 Trichloroethane CAS No 79-00-5 EINECS No 201-166-9 35. 1,1,2,2 Tetrachloroethane CAS No 79-34-5 EINECS No 201-197-8 36. 1,1,1,2 Tetrachloroethane CAS No 630-20-6 37. Pentachloroethane CAS No 76-01-7 EINECS No 200-925-1 38. 1,1 Dichloroethylene CAS No 75-35-4 EINECS No 200-864-0 39. 1,1,1 Trichloroethane, methyl chloroform CAS No 71-55-6 EINECS No 200-756-3	1. Shall not be used in concentrations equal to or greater than 0,1 % by weight in substances and ~~preparations~~ placed on the market for sale to the general public and/or in diffusive applications such as in surface cleaning and cleaning of fabrics. 2. Without prejudice to the application of other Community provisions on the classification, packaging and labelling of dangerous substances and ~~preparations,~~ the packaging of such substances and ~~preparations~~ containing them in concentrations equal to or greater than 0,1 % shall be legible and indelibly marked as follows: For use in industrial installations only. By way of derogation this provision shall not apply to: (a) medicinal or veterinary products as defined by Directive 2001/82/EC and Directive 2001/83/EC; (b) cosmetic products as defined by Directive 76/768/EEC.
	After	32. Chloroform CAS No 67-66-3 EINECS No 200-663-8 33. Carbon tetrachloride-tetrachloromethane CAS No 56-23-5 EINECS No 200-262-8 34. 1,1,2 Trichloroethane CAS No 79-00-5 EINECS No 201-166-9 35. 1,1,2,2 Tetrachloroethane CAS No 79-34-5 EINECS No 201-197-8 36. 1,1,1,2 Tetrachloroethane CAS No 630-20-6 37. Pentachloroethane CAS No 76-01-7 EINECS No 200-925-1 38. 1,1 Dichloroethylene CAS No 75-35-4 EINECS No 200-864-0 39. 1,1,1 Trichloroethane, methyl chloroform CAS No 71-55-6 EINECS No 200-756-3	1. Shall not be used in concentrations equal to or greater than 0,1 % by weight in substances and mixtures placed on the market for sale to the general public and/or in diffusive applications such as in surface cleaning and cleaning of fabrics. 2. Without prejudice to the application of other Community provisions on the classification, packaging and labelling of dangerous substances and mixtures, the packaging of such substances and mixtures containing them in concentrations equal to or greater than 0,1 % shall be legible and indelibly marked as follows: For use in industrial installations only. By way of derogation this provision shall not apply to: (a) medicinal or veterinary products as defined by Directive 2001/82/EC and Directive 2001/83/EC; (b) cosmetic products as defined by Directive 76/768/EEC.

Sources

CLP: every version the record holds; rows read from EUR-Lex consolidated version 02008R1272-20270101, in force 1 January 2027 (external, EUR-Lex)
Cosmetics Regulation: every version the record holds; rows read from EUR-Lex consolidated version 02009R1223-20260518, in force 18 May 2026 (external, EUR-Lex)
PIC Regulation: every version the record holds; rows read from EUR-Lex consolidated version 02012R0649-20261001, in force 1 October 2026 (external, EUR-Lex)
REACH: every version the record holds; rows read from EUR-Lex consolidated version 02006R1907-20260622, detected 11 September 2026 (external, EUR-Lex)

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