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CAS number

CAS 81-81-2 Warfarin

CAS 81-81-2 · CAS 5543-57-7 · CAS 5543-58-8 · EC 201-377-6 · EC 226-907-3 · EC 226-908-9 · Index No 607-056-00-0

Where CAS 81-81-2 appears: every table entry that prints it among its identifiers, in the newest version of each act this record holds, and every recorded change to those entries. Many entries name a group of substances and print no number, so absence here is not absence from the law. Not legal advice.

Where it appears now

CLP Annex VI section 3, Index No 607-056-00-0

Last changed in the version detected · Annex VI on this site

Annex VI section 3, table 1
Index NoChemical nameEC NoCAS NoClassificationLabellingSpecific Conc. Limits, M-factors and ATEs Notes
Hazard Class and Category Code(s)Hazard statement Code(s)Pictogram, Signal Word Code(s)Hazard statement Code(s)Suppl. Hazard statement Code(s)
607-056-00-0warfarin (ISO); 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one; [1] (S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone; [2] (R)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone [3]201-377-6 [1] 226-907-3 [2] 226-908-9 [3]81-81-2 [1] 5543-57-7 [2] 5543-58-8 [3]Repr. 1A Acute Tox. 1 Acute Tox. 1 Acute Tox. 2 STOT RE 1 Aquatic Chronic 2H360D H330 H310 H300 H372 (blood) H411GHS08 GHS06 GHS09 DgrH360D H330 H310 H300 H372 (blood) H411Repr. 1A; H360D: C ≥ 0,003 % STOT RE 1; H372 (blood): C ≥ 0,5 % STOT RE 2; H373 (blood): 0,05 % ≤ C < 0,5 %

CLP Annex VI section 3, table 2, Index No 607-056-00-0

No change to this entry since the first version the record holds, in force 1 December 2010. · Annex VI on this site

Annex VI section 3, table 2
Index NoInternational Chemical IdentificationEC NoCAS NoClassificationLabellingConcentration LimitsNotes
607-056-00-0warfarin (ISO); [1] (S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone; [2] (R)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone [3]201-377-6 [1] 226-907-3 [2] 226-908-9 [3]81-81-2 [1] 5543-57-7 [2] 5543-58-8 [3]Repr. Cat. 1; R61 T; R48/25 R52-53T R: 61-48/25-52/53 S: 53-45-61E

Cosmetics Regulation Annex II, Reference number 203

No change to this entry since the first version the record holds, in force 11 July 2013. · Annex II on this site

Annex II, table 1
Reference numberSubstance identification
Chemical name/INNCAS numberEC number
abcd
203Warfarin (INN) and its salts81-81-2201-377-6

PIC Regulation Annex I, the entry for Warfarin

Last changed in the version in force , by Regulation (EU) 2024/3199, the act that change names · Annex I on this site

Annex I, table 1
ChemicalCAS NoEC NoCN code Subcategory Use limitation Countries for which no notification is required
Warfarin 81-81-2201-377-6ex29322090p(1)-p(2)b-b

PIC Regulation Annex I, table 2, the entry for Warfarin

Last changed in the version in force , by Regulation (EU) 2024/3199, the act that change names · Annex I on this site

Annex I, table 2
ChemicalCAS NoEC NoCN code Category Use limitation
Warfarin81-81-2201-377-6ex29322090pb

REACH Annex XVII appendix 5, Index No 607-056-00-0

Last changed in the version in force , by Regulation (EU) 2017/1510, the act that change names · Annex XVII on this site

Annex XVII appendix 5, table 1
SubstancesIndex NoEC NoCAS NoNotes
Warfarin (ISO); 4-hydroxy-3-(3-oxo-1- phenylbutyl)-2H-chromen-2-one; [1] (S)-4-hydroxy-3-(3-oxo- 1-phenylbutyl)-2-benzopyrone; [2] (R)-4-hydroxy-3-(3-oxo- 1-phenylbutyl)-2-benzopyrone [3]607-056-00-0201-377-6 [1] 226-907-3 [2] 226-908-9 [3]81-81-2 [1] 5543-57-7 [2] 5543-58-8 [3]

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Its history

· amended · CLP Annex VI section 3, Index No 607-056-00-0

Recorded in the version detected . The change on its version page

Amended entries, Annex VI section 3, table 1
IdentifiersVersionIndex NoInternational Chemical IdentificationEC NoCAS NoClassificationLabellingSpecific Conc. Limits, M-factorsNotes
Hazard Class and Category Code(s)Hazard statement Code(s)Pictogram, Signal Word Code(s)Hazard statement Code(s)Suppl. Hazard statement Code(s)
Index No 607-056-00-0CAS 5543-57-7CAS 5543-58-8CAS 81-81-2EC 201-377-6EC 226-907-3EC 226-908-9Before607-056-00-0warfarin (ISO); [1] (S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone; [2] (R)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone [3]201-377-6 [1] 226-907-3 [2] 226-908-9 [3]81-81-2 [1] 5543-57-7 [2] 5543-58-8 [3]Repr. 1A STOT RE 1 Aquatic Chronic 3H360D *** H372 ** H412GHS08 DgrH360D *** H372 ** H412
After607-056-00-0warfarin (ISO); 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one; [1] (S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone; [2] (R)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone [3]201-377-6 [1] 226-907-3 [2] 226-908-9 [3]81-81-2 [1] 5543-57-7 [2] 5543-58-8 [3]Repr. 1A Acute Tox. 1 Acute Tox. 1 Acute Tox. 2 STOT RE 1 Aquatic Chronic 2H360D H330 H310 H300 H372 (blood) H411GHS08 GHS06 GHS09 DgrH360D H330 H310 H300 H372 (blood) H411Repr. 1A; H360D: C ≥ 0,003 % STOT RE 1; H372 (blood): C ≥ 0,5 % STOT RE 2; H373 (blood): 0,05 % ≤ C < 0,5 %

· amended · PIC Regulation Annex I, the entry for Warfarin

Recorded in the version in force , by Regulation (EU) 2024/3199, the act that change names. The change on its version page

Amended entries, Annex I, table 1
IdentifiersVersionChemicalCAS NoEC NoCN code Subcategory Use limitation Countries for which no notification is required
WarfarinCAS 81-81-2EC 201-377-6BeforeWarfarin81-81-2201-377-6ex29322090p(1)b
AfterWarfarin81-81-2201-377-6ex29322090p(1)-p(2)b-b

· added · PIC Regulation Annex I, table 2, the entry for Warfarin

Recorded in the version in force , by Regulation (EU) 2024/3199, the act that change names. The change on its version page

Added entries, Annex I, table 2
IdentifiersChemicalCAS NoEC NoCN code Category Use limitation
WarfarinCAS 81-81-2EC 201-377-6Warfarin81-81-2201-377-6ex29322090pb

· amended · PIC Regulation Annex I, the entry for Warfarin

Recorded in the version in force , by Regulation (EU) 2022/643, the act that change names. The change on its version page

Amended entries, Annex I, table 1
IdentifiersVersionChemicalCAS NoEC NoCN code Subcategory Use limitation Countries for which no notification is required
WarfarinCAS 81-81-2EC 201-377-6BeforeWarfarin81-81-2201-377-629322090p(1)b
AfterWarfarin81-81-2201-377-6ex29322090p(1)b

· amended · REACH Annex XVII appendix 5, Index No 607-056-00-0

Recorded in the version in force , by Regulation (EU) 2017/1510, the act that change names. The change on its version page

Amended entries, Annex XVII appendix 5, table 1
IdentifiersVersionSubstancesIndex NoEC NoCAS NoNotes
Index No 607-056-00-0CAS 5543-57-7CAS 5543-58-8CAS 81-81-2EC 201-377-6EC 226-907-3EC 226-908-9BeforeWarfarin; 4-hydroxy-3-(3-oxo-1-phenylbutyl)coumarin607-056-00-0201-377-681-81-2
AfterWarfarin (ISO); 4-hydroxy-3-(3-oxo-1- phenylbutyl)-2H-chromen-2-one; [1] (S)-4-hydroxy-3-(3-oxo- 1-phenylbutyl)-2-benzopyrone; [2] (R)-4-hydroxy-3-(3-oxo- 1-phenylbutyl)-2-benzopyrone [3]607-056-00-0201-377-6[1] 226-907-3 [2] 226-908-9 [3]81-81-2[1] 5543-57-7 [2] 5543-58-8 [3]

· added · PIC Regulation Annex I, the entry for Warfarin

Recorded in the version in force , by Regulation (EU) No 1078/2014 and Regulation (EU) 2019/1701, the acts that change names. The change on its version page

Added entries, Annex I, table 1
IdentifiersChemicalCAS NoEinecs NoCN codeSubcategory Use limitation Countries for which no notification is required
WarfarinCAS 81-81-2EC 201-377-6Warfarin81-81-2201-377-629322090p(1)b

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