EC number
EC 274-357-8 sodium N-(hydroxymethyl)glycinate
CAS 70161-44-3 · EC 274-357-8 · Index No 607-746-00-1
Where EC 274-357-8 appears: every table entry that prints it among its identifiers, in the newest version of each act this record holds, and every recorded change to those entries. Many entries name a group of substances and print no number, so absence here is not absence from the law. Not legal advice.
Where it appears now
CLP Annex VI section 3, Index No 607-746-00-1
Last changed in the version in force , by Regulation (EU) 2020/1182, the act that change names · Annex VI on this site
| Index No | Chemical name | EC No | CAS No | Classification | Labelling | Specific Conc. Limits, M-factors and ATEs | Notes | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Hazard Class and Category Code(s) | Hazard statement Code(s) | Pictogram, Signal Word Code(s) | Hazard statement Code(s) | Suppl. Hazard statement Code(s) | ||||||
| 607-746-00-1 | sodium N-(hydroxymethyl)glycinate; [formaldehyde released from sodium N-(hydroxymethyl)glycinate] | 274-357-8 | 70161-44-3 | Carc. 1B Muta. 2 Acute Tox. 4 Acute Tox. 4 STOT SE 3 Skin Irrit. 2 Eye Irrit. 2 Skin Sens. 1 | H350 H341 H332 H302 H335 H315 H319 H317 | GHS08 GHS07 Dgr | H350 H341 H332 H302 H335 H315 H319 H317 | inhalation: ATE = 3 mg/L (dusts or mists) oral: ATE = 1100 mg/kg bw | 8 9 | |
Cosmetics Regulation Annex II, Reference number 1669
Last changed in the version in force , by Regulation (EU) 2021/1902 and Regulation (EU) 2022/135, the acts that change names · Annex II on this site
| Reference number | Substance identification | ||
|---|---|---|---|
| Chemical name/INN | CAS number | EC number | |
| a | b | c | d |
| 1669 | Sodium N-(hydroxymethyl)glycinate; [formaldehyde released from sodium N-(hydroxymethyl)glycinate] if the maximum theoretical concentration of releasable formaldehyde, irrespective of the source, in the mixture as placed on the market is ≥ 0,1 % w/w | 70161-44-3 | 274-357-8 |
Cosmetics Regulation Annex V, Reference number 51
Last changed in the version in force , by Regulation (EU) 2022/1531 and Regulation (EU) 2022/2195, the acts that change names · Annex V on this site
| Reference number | Substance identification | Conditions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|
| Chemical name/INN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, Body parts | Maximum concentration in ready for use preparation | Other | ||
| a | b | c | d | e | f | g | h | i |
| 51 | Sodium N-(hydroxymethyl) glycinate | Sodium Hydroxymethylglycinate | 70161-44-3 | 274-357-8 | 0,5 % | Not to be used unless it can be shown that the maximum theoretical concentration of releasable formaldehyde, irrespective of the source, in the mixture as placed on the market is < 0,1 % w/w | ||
REACH Annex XVII appendix 2, Index No 607-746-00-1
Last changed in the version in force , by Regulation (EU) 2021/2204, the act that change names · Annex XVII on this site
| Substances | Index No | EC No | CAS No | Notes |
|---|---|---|---|---|
| Sodium N-(hydroxymethyl)glycinate; [formaldehyde released from sodium N-(hydroxymethyl)glycinate] | 607-746-00-1 | 274-357-8 | 70161-44-3 |
Look up a number
Type a CAS or EC number, with or without its hyphens, or an Index No into the search box at the top of the page: it reads 50000 as CAS 50-00-0. Every number is also listed by act on the substances page.
Its history
· amended · Cosmetics Regulation Annex V, Reference number 51
Recorded in the version in force , by Regulation (EU) 2022/1531 and Regulation (EU) 2022/2195, the acts that change names. Only spacing, dash forms or accents differ. The change on its version page
| Identifiers | Version | Reference number | Substance identification | Conditions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Chemical name/INN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, Body parts | Maximum concentration in ready for use preparation | Other | ||||
| a | b | c | d | e | f | g | h | i | ||
| Reference number 51CAS 70161-44-3EC 274-357-8 | Before | 51 | Sodium | Sodium Hydroxymethylglycinate | 70161-44-3 | 274-357-8 | 0,5 % | Not to be used unless it can be shown that the maximum theoretical concentration of releasable formaldehyde, irrespective of the source, in the mixture as placed on the market is < 0,1 % w/w | ||
| After | 51 | Sodium N-(hydroxymethyl) glycinate | Sodium Hydroxymethylglycinate | 70161-44-3 | 274-357-8 | 0,5 % | Not to be used unless it can be shown that the maximum theoretical concentration of releasable formaldehyde, irrespective of the source, in the mixture as placed on the market is < 0,1 % w/w | |||
· amended · Cosmetics Regulation Annex V, Reference number 51
Recorded in the version in force , by Regulation (EU) 2022/1531, the act that change names. The change on its version page
| Identifiers | Version | Reference number | Substance identification | Conditions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Chemical name/INN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, Body parts | Maximum concentration in ready for use preparation | Other | ||||
| a | b | c | d | e | f | g | h | i | ||
| Reference number 51CAS 70161-44-3EC 274-357-8 | Before | 51 | Sodium | Sodium Hydroxymethylglycinate | 70161-44-3 | 274-357-8 | 0,5 % | Not to be used | ||
| After | 51 | Sodium N-(hydroxymethyl)glycinate | Sodium Hydroxymethylglycinate | 70161-44-3 | 274-357-8 | 0,5 % | Not to be used unless it can be shown that the maximum theoretical concentration of releasable formaldehyde, irrespective of the source, in the mixture as placed on the market is < 0,1 % w/w | |||
· added · CLP Annex VI section 3, Index No 607-746-00-1
Recorded in the version in force , by Regulation (EU) 2020/1182, the act that change names. The change on its version page
| Identifiers | Index No | Chemical name | EC No | CAS No | Classification | Labelling | Specific Conc. Limits, M-factors and ATEs | Notes | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Hazard Class and Category Code(s) | Hazard statement Code(s) | Pictogram, Signal Word Code(s) | Hazard statement Code(s) | Suppl. Hazard statement Code(s) | |||||||
| Index No 607-746-00-1CAS 70161-44-3EC 274-357-8 | 607-746-00-1 | sodium N-(hydroxymethyl)glycinate; [formaldehyde released from sodium N-(hydroxymethyl)glycinate] | 274-357-8 | 70161-44-3 | Carc. 1B Muta. 2 Acute Tox. 4 Acute Tox. 4 STOT SE 3 Skin Irrit. 2 Eye Irrit. 2 Skin Sens. 1 | H350 H341 H332 H302 H335 H315 H319 H317 | GHS08 GHS07 Dgr | H350 H341 H332 H302 H335 H315 H319 H317 | inhalation: ATE = 3 mg/L (dusts or mists) oral: ATE = 1100 mg/kg bw | 8 9 | |
· added · Cosmetics Regulation Annex II, Reference number 1669
Recorded in the version in force , by Regulation (EU) 2021/1902 and Regulation (EU) 2022/135, the acts that change names. The change on its version page
| Identifiers | Reference number | Substance identification | ||
|---|---|---|---|---|
| Chemical name/INN | CAS number | EC number | ||
| a | b | c | d | |
| Reference number 1669CAS 70161-44-3EC 274-357-8 | 1669 | Sodium N-(hydroxymethyl)glycinate; [formaldehyde released from sodium N-(hydroxymethyl)glycinate] if the maximum theoretical concentration of releasable formaldehyde, irrespective of the source, in the mixture as placed on the market is ≥ 0,1 % w/w | 70161-44-3 | 274-357-8 |
· amended · Cosmetics Regulation Annex V, Reference number 51
Recorded in the version in force , by Regulation (EU) 2021/1902 and Regulation (EU) 2022/135, the acts that change names. The change on its version page
| Identifiers | Version | Reference number | Substance identification | Conditions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Chemical name/INN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, Body parts | Maximum concentration in ready for use preparation | Other | ||||
| a | b | c | d | e | f | g | h | i | ||
| Reference number 51CAS 70161-44-3EC 274-357-8 | Before | 51 | Sodium hydroxymethylamino acetate | Sodium Hydroxymethylglycinate | 70161-44-3 | 274-357-8 | 0,5 % | |||
| After | 51 | Sodium hydroxymethylamino acetate | Sodium Hydroxymethylglycinate | 70161-44-3 | 274-357-8 | 0,5 % | Not to be used if the maximum theoretical concentration of releasable formaldehyde, irrespective of the source, if the mixture as placed on the market is ≥ 0,1 % w/w | |||
· added · REACH Annex XVII appendix 2, Index No 607-746-00-1
Recorded in the version in force , by Regulation (EU) 2021/2204, the act that change names. The change on its version page
| Identifiers | Substances | Index No | EC No | CAS No | Notes |
|---|---|---|---|---|---|
| Index No 607-746-00-1CAS 70161-44-3EC 274-357-8 | Sodium N-(hydroxymethyl)glycinate; [formaldehyde released from sodium N-(hydroxymethyl)glycinate] | 607-746-00-1 | 274-357-8 | 70161-44-3 |
Sources
- CLP: every version the record holds; rows read from EUR-Lex consolidated version 02008R1272-20270101, in force 1 January 2027 (external, EUR-Lex)
- Cosmetics Regulation: every version the record holds; rows read from EUR-Lex consolidated version 02009R1223-20260518, in force 18 May 2026 (external, EUR-Lex)
- REACH: every version the record holds; rows read from EUR-Lex consolidated version 02006R1907-20260622, detected 11 September 2026 (external, EUR-Lex)