EC number
EC 212-828-1 1-methyl-2-pyrrolidone
CAS 872-50-4 · EC 212-828-1 · Index No 606-021-00-7
Where EC 212-828-1 appears: every table entry that prints it among its identifiers, in the newest version of each act this record holds, and every recorded change to those entries. Many entries name a group of substances and print no number, so absence here is not absence from the law. Not legal advice.
Where it appears now
CLP Annex VI section 3, Index No 606-021-00-7
Last changed in the version detected · Annex VI on this site
| Index No | Chemical name | EC No | CAS No | Classification | Labelling | Specific Conc. Limits, M-factors and ATEs | Notes | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Hazard Class and Category Code(s) | Hazard statement Code(s) | Pictogram, Signal Word Code(s) | Hazard statement Code(s) | Suppl. Hazard statement Code(s) | ||||||
| 606-021-00-7 | N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone | 212-828-1 | 872-50-4 | Repr. 1B STOT SE 3 Skin Irrit. 2 Eye Irrit. 2 | H360D*** H335 H315 H319 | GHS08 GHS07 Dgr | H360D*** H335 H315 H319 | STOT SE 3; H335: C ≥ 10 % | ||
CLP Annex VI section 3, table 2, Index No 606-021-00-7
Last changed in the version in force , by Regulation (EC) No 790/2009, the act that change names · Annex VI on this site
| Index No | International Chemical Identification | EC No | CAS No | Classification | Labelling | Concentration Limits | Notes |
|---|---|---|---|---|---|---|---|
| 606-021-00-7 | N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone | 212-828-1 | 872-50-4 | Repr. Cat. 2; R61 Xi; R36/37/38 | T R: 61-36/37/38 S: 53-45 | Repr. Cat. 2; R61: C ≥ 5 % Xi; R36/37/38: C ≥ 10 % |
Cosmetics Regulation Annex II, Reference number 1393
Last changed in the version in force , by Regulation (EU) 2019/831 and 5 others, the acts that change names · Annex II on this site
| Reference number | Substance identification | ||
|---|---|---|---|
| Chemical name/INN | CAS number | EC number | |
| a | b | c | d |
| 1393 | N-Methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone | 872-50-4 | 212-828-1 |
Plant Protection Products Regulation Annex III, No 9
Last changed in the version in force , by Regulation (EU) 2019/1381 and Regulation (EU) 2021/383, the acts that change names · Annex III on this site
| No | Name | EC names/Other names | CAS number | EC number | Classification/Other properties |
|---|---|---|---|---|---|
| 9. | 1-Methylpyrrolidin-2-one | 1-Methyl-2-pyrrolidone; 2-Pyrrolidinone, 1-methyl- | 872-50-4 | 212-828-1 | Toxic to reproduction cat.1B |
REACH Annex XVII, Entry 71
Last changed in the version in force , by Regulation (EU) 2018/589 and Regulation (EU) 2018/588, the acts that change names · Annex XVII on this site
| Column 1 Designation of the substance, of the group of substances or of the mixture | Column 2 Conditions of restriction |
|---|---|
| 71. 1-methyl-2-pyrrolidone (NMP) CAS No 872-50-4 EC No 212-828-1 | 1. Shall not be placed on the market as a substance on its own or in mixtures in a concentration equal to or greater than 0,3 % after 9 May 2020 unless manufacturers, importers and downstream users have included in the relevant chemical safety reports and safety data sheets, Derived No-Effect Levels (DNELs) relating to exposure of workers of 14,4 mg/m3 for exposure by inhalation and 4,8 mg/kg/day for dermal exposure. 2. Shall not be manufactured, or used, as a substance on its own or in mixtures in a concentration equal to or greater than 0,3 % after 9 May 2020 unless manufacturers and downstream users take the appropriate risk management measures and provide the appropriate operational conditions to ensure that exposure of workers is below the DNELs specified in paragraph 1. 3. By way of derogation from paragraphs 1 and 2, the obligations laid down therein shall apply from 9 May 2024 in relation to placing on the market for use, or use, as a solvent or reactant in the process of coating wires. |
REACH Annex XVII appendix 6, Index No 606-021-00-7
Last changed in the version in force , by Regulation (EU) No 125/2012 and 2 others, the acts that change names · Annex XVII on this site
| Substances | Index No | EC No | CAS No | Notes |
|---|---|---|---|---|
| N-methyl-2-pyrrolidone; 1-Methyl-2-pyrrolidone | 606-021-00-7 | 212-828-1 | 872-50-4 |
REACH Annex XVII appendix 12, the entry for N-methyl-2-pyrrolidone
Last changed in the version in force , by Regulation (EU) 2018/1513 and Regulation (EU) 2018/675, the acts that change names · Annex XVII on this site
| Substances | Index- No | CAS No | EC No | Concentration limit by weight |
|---|---|---|---|---|
| N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone (NMP) | 606-021-00-7 | 872-50-4 | 212-828-1 | 3000 mg/kg |
Look up a number
Type a CAS or EC number, with or without its hyphens, or an Index No into the search box at the top of the page: it reads 50000 as CAS 50-00-0. Every number is also listed by act on the substances page.
Its history
· amended · CLP Annex VI section 3, Index No 606-021-00-7
Recorded in the version detected . The change on its version page
| Identifiers | Version | Index No | International Chemical Identification | EC No | CAS No | Classification | Labelling | Specific Conc. Limits, M-factors | Notes | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hazard Class and Category Code(s) | Hazard statement Code(s) | Pictogram, Signal Word Code(s) | Hazard statement Code(s) | Suppl. Hazard statement Code(s) | ||||||||
| Index No 606-021-00-7CAS 872-50-4EC 212-828-1 | Before | 606-021-00-7 | N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone | 212-828-1 | 872-50-4 | Repr. 1B
| H360D***
| GHS08 GHS07 Dgr | H360D***
| |||
| After | 606-021-00-7 | N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone | 212-828-1 | 872-50-4 | Repr. 1B STOT SE 3 Skin Irrit. 2Eye Irrit. 2 | H360D*** H335 H315H319 | GHS08 GHS07 Dgr | H360D*** H335 H315H319 | STOT SE 3; H335: C ≥ 10 % | |||
· added · Plant Protection Products Regulation Annex III, No 9
Recorded in the version in force , by Regulation (EU) 2019/1381 and Regulation (EU) 2021/383, the acts that change names. The change on its version page
| Identifiers | No | Name | EC names/Other names | CAS number | EC number | Classification/Other properties |
|---|---|---|---|---|---|---|
| No 9CAS 872-50-4EC 212-828-1 | 9. | 1-Methylpyrrolidin-2-one | 1-Methyl-2-pyrrolidone; 2-Pyrrolidinone, 1-methyl- | 872-50-4 | 212-828-1 | Toxic to reproduction cat.1B |
· added · Cosmetics Regulation Annex II, Reference number 1393
Recorded in the version in force , by Regulation (EU) 2019/831 and 5 others, the acts that change names. The change on its version page
| Identifiers | Reference number | Substance identification | ||
|---|---|---|---|---|
| Chemical name/INN | CAS number | EC number | ||
| a | b | c | d | |
| Reference number 1393CAS 872-50-4EC 212-828-1 | 1393 | N-Methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone | 872-50-4 | 212-828-1 |
· added · REACH Annex XVII appendix 12, the entry for N-methyl-2-pyrrolidone
Recorded in the version in force , by Regulation (EU) 2018/1513 and Regulation (EU) 2018/675, the acts that change names. The change on its version page
| Identifiers | Substances | Index- No | CAS No | EC No | Concentration limit by weight |
|---|---|---|---|---|---|
| N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone (NMP)CAS 872-50-4EC 212-828-1Index No 606-021-00-7 | N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone (NMP) | 606-021-00-7 | 872-50-4 | 212-828-1 | 3000 mg/kg |
· added · REACH Annex XVII, Entry 71
Recorded in the version in force , by Regulation (EU) 2018/589 and Regulation (EU) 2018/588, the acts that change names. The change on its version page
| Identifiers | Column 1 Designation of the substance, of the group of substances or of the mixture | Column 2 Conditions of restriction |
|---|---|---|
| Entry 71CAS 872-50-4EC 212-828-1 | 71. 1-methyl-2-pyrrolidone (NMP) CAS No 872-50-4 EC No 212-828-1 | 1. Shall not be placed on the market as a substance on its own or in mixtures in a concentration equal to or greater than 0,3 % after 9 May 2020 unless manufacturers, importers and downstream users have included in the relevant chemical safety reports and safety data sheets, Derived No-Effect Levels (DNELs) relating to exposure of workers of 14,4 mg/m3 for exposure by inhalation and 4,8 mg/kg/day for dermal exposure. 2. Shall not be manufactured, or used, as a substance on its own or in mixtures in a concentration equal to or greater than 0,3 % after 9 May 2020 unless manufacturers and downstream users take the appropriate risk management measures and provide the appropriate operational conditions to ensure that exposure of workers is below the DNELs specified in paragraph 1. 3. By way of derogation from paragraphs 1 and 2, the obligations laid down therein shall apply from 9 May 2024 in relation to placing on the market for use, or use, as a solvent or reactant in the process of coating wires. |
· added · REACH Annex XVII appendix 6, Index No 606-021-00-7
Recorded in the version in force , by Regulation (EU) No 125/2012 and 2 others, the acts that change names. The change on its version page
| Identifiers | Substances | Index No | EC No | CAS No | Notes |
|---|---|---|---|---|---|
| Index No 606-021-00-7CAS 872-50-4EC 212-828-1 | N-methyl-2-pyrrolidone; 1-Methyl-2-pyrrolidone | 606-021-00-7 | 212-828-1 | 872-50-4 |
· amended · CLP Annex VI section 3, Index No 606-021-00-7
Recorded in the version in force , by Regulation (EC) No 790/2009, the act that change names. The change on its version page
| Identifiers | Version | Index No | International Chemical Identification | EC No | CAS No | Classification | Labelling | Specific Conc. Limits, M-factors | Notes | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hazard Class and Category Code(s) | Hazard statement Code(s) | Pictogram, Signal Word Code(s) | Hazard statement Code(s) | Suppl. Hazard statement Code(s) | ||||||||
| Index No 606-021-00-7CAS 872-50-4EC 212-828-1 | Before | 606-021-00-7 | 212-828-1 | 872-50-4 | Eye Irrit. 2 Skin Irrit. 2 | H319 H315 | GHS07
| H319 H315 | ||||
| After | 606-021-00-7 | N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone | 212-828-1 | 872-50-4 | Repr. 1B Eye Irrit. 2 STOT SE 3 Skin Irrit. 2 | H360D*** H319 H335 H315 | GHS08 GHS07 Dgr | H360D*** H319 H335 H315 | Repr. 1B; H360D: C ≥ 5 % STOT SE 3; H335: C ≥ 10 % | |||
· amended · CLP Annex VI section 3, table 2, Index No 606-021-00-7
Recorded in the version in force , by Regulation (EC) No 790/2009, the act that change names. The change on its version page
| Identifiers | Version | Index No | International Chemical Identification | EC No | CAS No | Classification | Labelling | Concentration Limits | Notes |
|---|---|---|---|---|---|---|---|---|---|
| Index No 606-021-00-7CAS 872-50-4EC 212-828-1 | Before | 606-021-00-7 | 212-828-1 | 872-50-4 | Xi; | Xi; | |||
| After | 606-021-00-7 | N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone | 212-828-1 | 872-50-4 | Repr. Cat. 2; R61 Xi; R36/37/38 | T R: 61-36/37/38 S: 53-45 | Repr. Cat. 2; R61: C ≥ 5 % Xi; R36/37/38: C ≥ 10 % |
Sources
- CLP: every version the record holds; rows read from EUR-Lex consolidated version 02008R1272-20270101, in force 1 January 2027 (external, EUR-Lex)
- Cosmetics Regulation: every version the record holds; rows read from EUR-Lex consolidated version 02009R1223-20260518, in force 18 May 2026 (external, EUR-Lex)
- Plant Protection Products Regulation: every version the record holds; rows read from EUR-Lex consolidated version 02009R1107-20260616, in force 16 June 2026 (external, EUR-Lex)
- REACH: every version the record holds; rows read from EUR-Lex consolidated version 02006R1907-20260622, detected 11 September 2026 (external, EUR-Lex)