CAS number
CAS 2687-91-4 N-ethyl-2-pyrrolidone
CAS 2687-91-4 · EC 220-250-6 · Index No 616-208-00-5
Where CAS 2687-91-4 appears: every table entry that prints it among its identifiers, in the newest version of each act this record holds, and every recorded change to those entries. Many entries name a group of substances and print no number, so absence here is not absence from the law. Not legal advice.
Where it appears now
CLP Annex VI section 3, Index No 616-208-00-5
Last changed in the version detected · Annex VI on this site
| Index No | Chemical name | EC No | CAS No | Classification | Labelling | Specific Conc. Limits, M-factors and ATEs | Notes | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Hazard Class and Category Code(s) | Hazard statement Code(s) | Pictogram, Signal Word Code(s) | Hazard statement Code(s) | Suppl. Hazard statement Code(s) | ||||||
| 616-208-00-5 | N-ethyl-2-pyrrolidone; 1-ethylpyrrolidin-2-one | 220-250-6 | 2687-91-4 | Repr. 1B | H360D | GHS08 Dgr | H360D | |||
CLP Annex VI section 3, table 2, Index No 616-208-00-5
Last changed in the version detected · Annex VI on this site
| Index No | International Chemical Identification | EC No | CAS No | Classification | Labelling | Concentration Limits | Notes |
|---|---|---|---|---|---|---|---|
| 616-208-00-5 | N-ethyl-2-pyrrolidone; 1-ethylpyrrolidin-2-one | 220-250-6 | 2687-91-4 | Repr. Cat. 2; R61 | T R: 61 S: 45-53 |
Cosmetics Regulation Annex II, Reference number 1562
Last changed in the version in force , by Regulation (EU) 2019/831 and 5 others, the acts that change names · Annex II on this site
| Reference number | Substance identification | ||
|---|---|---|---|
| Chemical name/INN | CAS number | EC number | |
| a | b | c | d |
| 1562 | N-Ethyl-2-pyrrolidone; 1-ethylpyrrolidin-2-one | 2687-91-4 | 220-250-6 |
Plant Protection Products Regulation Annex III, No 5
Last changed in the version in force , by Regulation (EU) 2019/1381 and Regulation (EU) 2021/383, the acts that change names · Annex III on this site
| No | Name | EC names/Other names | CAS number | EC number | Classification/Other properties |
|---|---|---|---|---|---|
| 5. | 1-Ethylpyrrolidin-2-one | 1-Ethylpyrrolidin-2-one; N-ethyl-2-pyrrolidone | 2687-91-4 | 220-250-6 | Toxic to reproduction cat.1B |
REACH Annex XVII, Entry 81
Last changed in the version in force , by Regulation (EU) 2025/1090, the act that change names · Annex XVII on this site
| Column 1 Designation of the substance, of the group of substances or of the mixture | Column 2 Conditions of restriction |
|---|---|
| 81. 1-ethylpyrrolidin-2-one (NEP) CAS No 2687-91-4 EC No 220-250-6 | 1. Shall not be placed on the market as a substance on its own, as a constituent of other substances, or in mixtures in a concentration equal to or greater than 0,3 % after 23 December 2026 unless manufacturers, importers and downstream users have included in the relevant chemical safety reports and safety data sheets, derived no-effect levels (DNELs) relating to exposure of workers of 4,0 mg/m3 for long-term exposure by inhalation and 2,4 mg/kg bw/day for long-term dermal exposure. 2. Shall not be manufactured, or used, as a substance on its own, as a constituent of other substances, or in mixtures in a concentration equal to or greater than 0,3 % after 23 December 2026 unless manufacturers and downstream users take the appropriate risk management measures and provide the appropriate operational conditions to ensure that exposure of workers is below the DNELs specified in paragraph 1. |
REACH Annex XVII appendix 6, Index No 616-208-00-5
Last changed in the version in force , by Regulation (EU) No 317/2014, the act that change names · Annex XVII on this site
| Substances | Index No | EC No | CAS No | Notes |
|---|---|---|---|---|
| N-ethyl-2-pyrrolidone; 1-ethylpyrrolidin-2-one | 616-208-00-5 | 220-250-6 | 2687-91-4 |
Look up a number
Type a CAS or EC number, with or without its hyphens, or an Index No into the search box at the top of the page: it reads 50000 as CAS 50-00-0. Every number is also listed by act on the substances page.
Its history
· added · CLP Annex VI section 3, Index No 616-208-00-5
Recorded in the version detected . The change on its version page
| Identifiers | Index No | International Chemical Identification | EC No | CAS No | Classification | Labelling | Specific Conc. Limits, M-factors | Notes | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Hazard Class and Category Code(s) | Hazard statement Code(s) | Pictogram, Signal Word Code(s) | Hazard statement Code(s) | Suppl. Hazard statement Code(s) | |||||||
| Index No 616-208-00-5CAS 2687-91-4EC 220-250-6 | 616-208-00-5 | N-ethyl-2-pyrrolidone; 1-ethylpyrrolidin-2-one | 220-250-6 | 2687-91-4 | Repr. 1B | H360D | GHS08 Dgr | H360D | |||
· added · CLP Annex VI section 3, table 2, Index No 616-208-00-5
Recorded in the version detected . The change on its version page
| Identifiers | Index No | International Chemical Identification | EC No | CAS No | Classification | Labelling | Concentration Limits | Notes |
|---|---|---|---|---|---|---|---|---|
| Index No 616-208-00-5CAS 2687-91-4EC 220-250-6 | 616-208-00-5 | N-ethyl-2-pyrrolidone; 1-ethylpyrrolidin-2-one | 220-250-6 | 2687-91-4 | Repr. Cat. 2; R61 | T R: 61 S: 45-53 |
· added · REACH Annex XVII, Entry 81
Recorded in the version in force , by Regulation (EU) 2025/1090, the act that change names. The change on its version page
| Identifiers | Column 1 Designation of the substance, of the group of substances or of the mixture | Column 2 Conditions of restriction |
|---|---|---|
| Entry 81CAS 2687-91-4EC 220-250-6 | 81. 1-ethylpyrrolidin-2-one (NEP) CAS No 2687-91-4 EC No 220-250-6 | 1. Shall not be placed on the market as a substance on its own, as a constituent of other substances, or in mixtures in a concentration equal to or greater than 0,3 % after 23 December 2026 unless manufacturers, importers and downstream users have included in the relevant chemical safety reports and safety data sheets, derived no-effect levels (DNELs) relating to exposure of workers of 4,0 mg/m3 for long-term exposure by inhalation and 2,4 mg/kg bw/day for long-term dermal exposure. 2. Shall not be manufactured, or used, as a substance on its own, as a constituent of other substances, or in mixtures in a concentration equal to or greater than 0,3 % after 23 December 2026 unless manufacturers and downstream users take the appropriate risk management measures and provide the appropriate operational conditions to ensure that exposure of workers is below the DNELs specified in paragraph 1. |
· added · Plant Protection Products Regulation Annex III, No 5
Recorded in the version in force , by Regulation (EU) 2019/1381 and Regulation (EU) 2021/383, the acts that change names. The change on its version page
| Identifiers | No | Name | EC names/Other names | CAS number | EC number | Classification/Other properties |
|---|---|---|---|---|---|---|
| No 5CAS 2687-91-4EC 220-250-6 | 5. | 1-Ethylpyrrolidin-2-one | 1-Ethylpyrrolidin-2-one; N-ethyl-2-pyrrolidone | 2687-91-4 | 220-250-6 | Toxic to reproduction cat.1B |
· added · Cosmetics Regulation Annex II, Reference number 1562
Recorded in the version in force , by Regulation (EU) 2019/831 and 5 others, the acts that change names. The change on its version page
| Identifiers | Reference number | Substance identification | ||
|---|---|---|---|---|
| Chemical name/INN | CAS number | EC number | ||
| a | b | c | d | |
| Reference number 1562CAS 2687-91-4EC 220-250-6 | 1562 | N-Ethyl-2-pyrrolidone; 1-ethylpyrrolidin-2-one | 2687-91-4 | 220-250-6 |
· added · REACH Annex XVII appendix 6, Index No 616-208-00-5
Recorded in the version in force , by Regulation (EU) No 317/2014, the act that change names. The change on its version page
| Identifiers | Substances | Index No | EC No | CAS No | Notes |
|---|---|---|---|---|---|
| Index No 616-208-00-5CAS 2687-91-4EC 220-250-6 | N-ethyl-2-pyrrolidone; 1-ethylpyrrolidin-2-one | 616-208-00-5 | 220-250-6 | 2687-91-4 |
Sources
- CLP: every version the record holds; rows read from EUR-Lex consolidated version 02008R1272-20270101, in force 1 January 2027 (external, EUR-Lex)
- Cosmetics Regulation: every version the record holds; rows read from EUR-Lex consolidated version 02009R1223-20260518, in force 18 May 2026 (external, EUR-Lex)
- Plant Protection Products Regulation: every version the record holds; rows read from EUR-Lex consolidated version 02009R1107-20260616, in force 16 June 2026 (external, EUR-Lex)
- REACH: every version the record holds; rows read from EUR-Lex consolidated version 02006R1907-20260622, detected 11 September 2026 (external, EUR-Lex)