EC number
EC 204-826-4 N,N-dimethylacetamide
CAS 127-19-5 · EC 204-826-4 · Index No 616-011-00-4
Where EC 204-826-4 appears: every table entry that prints it among its identifiers, in the newest version of each act this record holds, and every recorded change to those entries. Many entries name a group of substances and print no number, so absence here is not absence from the law. Not legal advice.
Where it appears now
CLP Annex VI section 3, Index No 616-011-00-4
Last changed in the version detected · Annex VI on this site
| Index No | Chemical name | EC No | CAS No | Classification | Labelling | Specific Conc. Limits, M-factors and ATEs | Notes | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Hazard Class and Category Code(s) | Hazard statement Code(s) | Pictogram, Signal Word Code(s) | Hazard statement Code(s) | Suppl. Hazard statement Code(s) | ||||||
| 616-011-00-4 | N,N-dimethylacetamide | 204-826-4 | 127-19-5 | Repr. 1B Acute Tox. 4* Acute Tox. 4* | H360D*** H332 H312 | GHS08 GHS07 Dgr | H360D*** H332 H312 | |||
Cosmetics Regulation Annex II, Reference number 747
No change to this entry since the first version the record holds, in force 11 July 2013. · Annex II on this site
| Reference number | Substance identification | ||
|---|---|---|---|
| Chemical name/INN | CAS number | EC number | |
| a | b | c | d |
| 747 | N,N-Dimethylacetamide | 127-19-5 | 204-826-4 |
REACH Annex XVII, Entry 80
Last changed in the version in force , by Regulation (EU) 2025/1090, the act that change names · Annex XVII on this site
| Column 1 Designation of the substance, of the group of substances or of the mixture | Column 2 Conditions of restriction |
|---|---|
| 80. N,N-dimethylacetamide (DMAC) CAS No 127-19-5 EC No 204-826-4 | 1. Shall not be placed on the market as a substance on its own, as a constituent of other substances, or in mixtures in a concentration equal to or greater than 0,3 % after 23 December 2026 unless manufacturers, importers and downstream users have included in the relevant chemical safety reports and safety data sheets, derived no-effect levels (DNELs) relating to exposure of workers of 13 mg/m3 for long-term exposure by inhalation and 1,8 mg/kg bw/day for long-term dermal exposure. 2. Shall not be manufactured, or used, as a substance on its own, as a constituent of other substances, or in mixtures in a concentration equal to or greater than 0,3 % after 23 December 2026 unless manufacturers and downstream users take the appropriate risk management measures and provide the appropriate operational conditions to ensure that exposure of workers is below the DNELs specified in paragraph 1. 3. By way of derogation from paragraphs 1 and 2, the obligations laid down therein shall apply from 23 June 2029 in relation to placing on the market for use, or use, as a solvent in the production of man-made fibres. |
REACH Annex XVII appendix 6, Index No 616-011-00-4
No change to this entry since the first version the record holds, in force 12 October 2008. · Annex XVII on this site
| Substances | Index No | EC No | CAS No | Notes |
|---|---|---|---|---|
| N, N-Dimethylacetamide | 616-011-00-4 | 204-826-4 | 127-19-5 | E |
REACH Annex XVII appendix 12, the entry for N,N-dimethylacetamide (DMAC)
Last changed in the version in force , by Regulation (EU) 2018/1513 and Regulation (EU) 2018/675, the acts that change names · Annex XVII on this site
| Substances | Index- No | CAS No | EC No | Concentration limit by weight |
|---|---|---|---|---|
| N,N-dimethylacetamide (DMAC) | 616-011-00-4 | 127-19-5 | 204-826-4 | 3000 mg/kg |
Look up a number
Type a CAS or EC number, with or without its hyphens, or an Index No into the search box at the top of the page: it reads 50000 as CAS 50-00-0. Every number is also listed by act on the substances page.
Its history
· amended · CLP Annex VI section 3, Index No 616-011-00-4
Recorded in the version detected . The change on its version page
| Identifiers | Version | Index No | International Chemical Identification | EC No | CAS No | Classification | Labelling | Specific Conc. Limits, M-factors | Notes | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hazard Class and Category Code(s) | Hazard statement Code(s) | Pictogram, Signal Word Code(s) | Hazard statement Code(s) | Suppl. Hazard statement Code(s) | ||||||||
| Index No 616-011-00-4CAS 127-19-5EC 204-826-4 | Before | 616-011-00-4 | N,N-dimethylacetamide | 204-826-4 | 127-19-5 | Repr. 1B
Acute Tox. | GHS08 GHS07 Dgr | |||||
| After | 616-011-00-4 | N,N-dimethylacetamide | 204-826-4 | 127-19-5 | Repr. 1B Acute Tox. 4* Acute Tox. 4* | H360D*** H332 H312 | GHS08 GHS07 Dgr | H360D*** H332 H312 | ||||
· removed · CLP Annex VI section 3, table 2, Index No 616-011-00-4
Recorded in the version detected . The change on its version page
| Identifiers | Index No | International Chemical Identification | EC No | CAS No | Classification | Labelling | Concentration Limits | Notes |
|---|---|---|---|---|---|---|---|---|
| Index No 616-011-00-4CAS 127-19-5EC 204-826-4 | 616-011-00-4 | N,N-dimethylacetamide | 204-826-4 | 127-19-5 | Repr. Cat. 2; R61 Xn; R20/21 | T R: 61-20/21 S: 53-45 | Repr. Cat. 2; R61: C ≥ 5 % | E |
· added · REACH Annex XVII, Entry 80
Recorded in the version in force , by Regulation (EU) 2025/1090, the act that change names. The change on its version page
| Identifiers | Column 1 Designation of the substance, of the group of substances or of the mixture | Column 2 Conditions of restriction |
|---|---|---|
| Entry 80CAS 127-19-5EC 204-826-4 | 80. N,N-dimethylacetamide (DMAC) CAS No 127-19-5 EC No 204-826-4 | 1. Shall not be placed on the market as a substance on its own, as a constituent of other substances, or in mixtures in a concentration equal to or greater than 0,3 % after 23 December 2026 unless manufacturers, importers and downstream users have included in the relevant chemical safety reports and safety data sheets, derived no-effect levels (DNELs) relating to exposure of workers of 13 mg/m3 for long-term exposure by inhalation and 1,8 mg/kg bw/day for long-term dermal exposure. 2. Shall not be manufactured, or used, as a substance on its own, as a constituent of other substances, or in mixtures in a concentration equal to or greater than 0,3 % after 23 December 2026 unless manufacturers and downstream users take the appropriate risk management measures and provide the appropriate operational conditions to ensure that exposure of workers is below the DNELs specified in paragraph 1. 3. By way of derogation from paragraphs 1 and 2, the obligations laid down therein shall apply from 23 June 2029 in relation to placing on the market for use, or use, as a solvent in the production of man-made fibres. |
· added · REACH Annex XVII appendix 12, the entry for N,N-dimethylacetamide (DMAC)
Recorded in the version in force , by Regulation (EU) 2018/1513 and Regulation (EU) 2018/675, the acts that change names. The change on its version page
| Identifiers | Substances | Index- No | CAS No | EC No | Concentration limit by weight |
|---|---|---|---|---|---|
| N,N-dimethylacetamide (DMAC)CAS 127-19-5EC 204-826-4Index No 616-011-00-4 | N,N-dimethylacetamide (DMAC) | 616-011-00-4 | 127-19-5 | 204-826-4 | 3000 mg/kg |
Sources
- CLP: every version the record holds; rows read from EUR-Lex consolidated version 02008R1272-20270101, in force 1 January 2027 (external, EUR-Lex)
- Cosmetics Regulation: every version the record holds; rows read from EUR-Lex consolidated version 02009R1223-20260518, in force 18 May 2026 (external, EUR-Lex)
- REACH: every version the record holds; rows read from EUR-Lex consolidated version 02006R1907-20260622, detected 11 September 2026 (external, EUR-Lex)