EC number
EC 203-404-7 p-phenylenediamine
CAS 106-50-3 · CAS 624-18-0 · CAS 16245-77-5 · EC 203-404-7 · EC 210-834-9 · EC 240-357-1 · Index No 612-028-00-6
Where EC 203-404-7 appears: every table entry that prints it among its identifiers, in the newest version of each act this record holds, and every recorded change to those entries. Many entries name a group of substances and print no number, so absence here is not absence from the law. Not legal advice.
Where it appears now
CLP Annex VI section 3, Index No 612-028-00-6
No change to this entry since the first version the record holds, in force 1 December 2010. · Annex VI on this site
| Index No | Chemical name | EC No | CAS No | Classification | Labelling | Specific Conc. Limits, M-factors and ATEs | Notes | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Hazard Class and Category Code(s) | Hazard statement Code(s) | Pictogram, Signal Word Code(s) | Hazard statement Code(s) | Suppl. Hazard statement Code(s) | ||||||
| 612-028-00-6 | p-phenylenediamine | 203-404-7 | 106-50-3 | Acute Tox. 3 * Acute Tox. 3 * Acute Tox. 3 * Eye Irrit. 2 Skin Sens. 1 Aquatic Acute 1 Aquatic Chronic 1 | H331 H311 H301 H319 H317 H400 H410 | GHS06 GHS09 Dgr | H331 H311 H301 H319 H317 H410 | |||
CLP Annex VI section 3, table 2, Index No 612-028-00-6
No change to this entry since the first version the record holds, in force 1 December 2010. · Annex VI on this site
| Index No | International Chemical Identification | EC No | CAS No | Classification | Labelling | Concentration Limits | Notes |
|---|---|---|---|---|---|---|---|
| 612-028-00-6 | p-phenylenediamine | 203-404-7 | 106-50-3 | T; R23/24/25 Xi; R36 R43 N; R50-53 | T+; N R: 23/24/25-36-43-50/53 S: (1/2-)28-36/37-45-60-61 |
Cosmetics Regulation Annex III, Reference number 8a
Last changed in the version in force , by Regulation (EU) No 344/2013 and Regulation (EU) No 1197/2013, the acts that change names · Annex III on this site
| Reference number | Substance identification | Restrictions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|
| Chemical name/INN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, body parts | Maximum concentration in ready for use preparation | Other | ||
| a | b | c | d | e | f | g | h | i |
| 8a | p-Phenylenediamine and its salts | p-Phenylenediamine; p-Phenylenediamine HCl; p-Phenylenediamine Sulphate | 106-50-3 / 624-18-0 / 16245-77-5 | 203-404-7 / 210-834-9 / 240-357-1 | Hair dye substance in oxidative hair dye products | (a) General use | (a) To be printed on the label: The mixing ratio. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows. | |
| (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2 % calculated as free base | (b) To be printed on the label: The mixing ratio. For professional use only. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains phenylenediamines. Wear suitable gloves. | |||||||
Cosmetics Regulation Annex III, Reference number 8b
Last changed in the version in force , by Regulation (EU) No 358/2014, the act that change names · Annex III on this site
| Reference number | Substance identification | Restrictions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|
| Chemical name/INN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, body parts | Maximum concentration in ready for use preparation | Other | ||
| a | b | c | d | e | f | g | h | i |
| 8b | p-Phenylenediamine and its salts | p-Phenylenediamine; p-Phenylenediamine HCl; p-Phenylenediamine Sulphate | 106-50-3 / 624-18-0 / 16245-77-5 | 203-404-7 / 210-834-9 / 240-357-1 | Products intended for colouring eyelashes | After mixing under oxidative conditions the maximum concentration applied to eyelashes must not exceed 2 % calculated as free base For professional use only. | To be printed on the label: The mixing ratio. For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: has a rash on the face or sensitive, irritated and damaged scalp, has experienced any reaction after colouring hair or eyelashes, has experienced a reaction to a temporary black henna tattoo in the past. Rinse eyes immediately if product comes into contact with them. Contains phenylenediamines. Wear suitable gloves. | |
REACH Annex XVII appendix 13, CAS No 106-50-3
Last changed in the version in force , by Regulation (EU) 2020/2081 and 3 others, the acts that change names · Annex XVII on this site
| Substance name | EC No | CAS No | Concentration limit (by weight) |
|---|---|---|---|
| p-Phenylenediamine | 203-404-7 | 106-50-3 | 0,0005 % |
Look up a number
Type a CAS or EC number, with or without its hyphens, or an Index No into the search box at the top of the page: it reads 50000 as CAS 50-00-0. Every number is also listed by act on the substances page.
Its history
· added · REACH Annex XVII appendix 13, CAS No 106-50-3
Recorded in the version in force , by Regulation (EU) 2020/2081 and 3 others, the acts that change names. The change on its version page
| Identifiers | Substance name | EC No | CAS No | Concentration limit (by weight) |
|---|---|---|---|---|
| CAS No 106-50-3CAS 106-50-3EC 203-404-7 | p-Phenylenediamine | 203-404-7 | 106-50-3 | 0,0005 % |
· amended · Cosmetics Regulation Annex III, Reference number 8b
Recorded in the version in force , by Regulation (EU) No 358/2014, the act that change names. The change on its version page
| Identifiers | Version | Reference number | Substance identification | Restrictions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Chemical name/INN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, body parts | Maximum concentration in ready for use preparation | Other | ||||
| a | b | c | d | e | f | g | h | i | ||
| Reference number 8bCAS 106-50-3CAS 16245-77-5CAS 624-18-0EC 203-404-7EC 210-834-9EC 240-357-1 | Before | 8b | p-Phenylenediamine and its salts | p-Phenylenediamine; p-Phenylenediamine HCl; p-Phenylenediamine Sulphate | 106-50-3 / 624-18-0 / 16245-77-5 | 203-404-7 / 210-834-9 / 240-357-1 | Products intended for colouring eyelashes | After mixing under oxidative conditions the maximum concentration applied to eyelashes must not exceed 2 % calculated as free base For professional use only. | ||
| After | 8b | p-Phenylenediamine and its salts | p-Phenylenediamine; p-Phenylenediamine HCl; p-Phenylenediamine Sulphate | 106-50-3 / 624-18-0 / 16245-77-5 | 203-404-7 / 210-834-9 / 240-357-1 | Products intended for colouring eyelashes | After mixing under oxidative conditions the maximum concentration applied to eyelashes must not exceed 2 % calculated as free base For professional use only. | To be printed on the label: The mixing ratio. For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: has a rash on the face or sensitive, irritated and damaged scalp, has experienced any reaction after colouring hair or eyelashes, has experienced a reaction to a temporary black henna tattoo in the past. Rinse eyes immediately if product comes into contact with them. Contains phenylenediamines. Wear suitable gloves. | ||
· added · Cosmetics Regulation Annex III, Reference number 8b
Recorded in the version in force , by Regulation (EU) No 483/2013, the act that change names. The change on its version page
| Identifiers | Reference number | Substance identification | Restrictions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|---|
| Chemical name/INN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, body parts | Maximum concentration in ready for use preparation | Other | |||
| a | b | c | d | e | f | g | h | i | |
| Reference number 8bCAS 106-50-3CAS 16245-77-5CAS 624-18-0EC 203-404-7EC 210-834-9EC 240-357-1 | 8b | p-Phenylenediamine and its salts | p-Phenylenediamine; p-Phenylenediamine HCl; p-Phenylenediamine Sulphate | 106-50-3 / 624-18-0 / 16245-77-5 | 203-404-7 / 210-834-9 / 240-357-1 | Products intended for colouring eyelashes | After mixing under oxidative conditions the maximum concentration applied to eyelashes must not exceed 2 % calculated as free base For professional use only. | ||
· amended · Cosmetics Regulation Annex III, Reference number 8
Recorded in the version in force , by Regulation (EU) No 344/2013 and Regulation (EU) No 1197/2013, the acts that change names. The change on its version page
| Identifiers | Version | Reference number | Substance identification | Restrictions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Chemical name/INN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, body parts | Maximum concentration in ready for use preparation | Other | ||||
| a | b | c | d | e | f | g | h | i | ||
| Reference number 8CAS 106-50-3EC 203-404-7 | Before | 8 | (a) General use
| (a) | ||||||
| (b) Professional use | (b) For professional use only
Contains | |||||||||
| After | 8 | N-substituted derivatives of p-Phenylenediamine and their salts; N-substituted derivatives of o-Phenylenediamine , with exception of those derivatives listed elsewhere in this Annex and under reference numbers 1309, 1311, and 1312 in Annex II | Hair dye substance in oxidative hair dye products | (a) General use | (a) To be printed on the label: The mixing ratio. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows | |||||
| (b) Professional useFor (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 3 % calculated as free base | (b) To be printed on the label: The mixing ratio. For professional use only Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains phenylenediamines. Wear suitable gloves | |||||||||
· added · Cosmetics Regulation Annex III, Reference number 8a
Recorded in the version in force , by Regulation (EU) No 344/2013 and Regulation (EU) No 1197/2013, the acts that change names. The change on its version page
| Identifiers | Reference number | Substance identification | Restrictions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|---|
| Chemical name/INN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, body parts | Maximum concentration in ready for use preparation | Other | |||
| a | b | c | d | e | f | g | h | i | |
| Reference number 8aCAS 106-50-3CAS 16245-77-5CAS 624-18-0EC 203-404-7EC 210-834-9EC 240-357-1 | 8a | p-Phenylenediamine and its salts | p-Phenylenediamine; p-Phenylenediamine HCl; p-Phenylenediamine Sulphate | 106-50-3 / 624-18-0 / 16245-77-5 | 203-404-7 / 210-834-9 / 240-357-1 | Hair dye substance in oxidative hair dye products | (a) General use | (a) To be printed on the label: The mixing ratio. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows. | |
| (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2 % calculated as free base | (b) To be printed on the label: The mixing ratio. For professional use only. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains phenylenediamines. Wear suitable gloves. | ||||||||
Sources
- CLP: every version the record holds; rows read from EUR-Lex consolidated version 02008R1272-20270101, in force 1 January 2027 (external, EUR-Lex)
- Cosmetics Regulation: every version the record holds; rows read from EUR-Lex consolidated version 02009R1223-20260518, in force 18 May 2026 (external, EUR-Lex)
- REACH: every version the record holds; rows read from EUR-Lex consolidated version 02006R1907-20260622, detected 11 September 2026 (external, EUR-Lex)