EC number

EC 202-453-1 4-methyl-m-phenylenediamine

CAS 95-80-7 · CAS 823-40-5 · CAS 25376-45-8 · EC 202-453-1 · EC 212-513-9 · EC 246-910-3 · Index No 612-099-00-3 · Index No 612-151-00-5

Where EC 202-453-1 appears: every table entry that prints it among its identifiers, in the newest version of each act this record holds, and every recorded change to those entries. Many entries name a group of substances and print no number, so absence here is not absence from the law. Not legal advice.

Where it appears now

CLP Annex VI section 3, Index No 612-099-00-3

Last changed in the version in force 1 December 2010, by Regulation (EC) No 790/2009, the act that change names · Annex VI on this site

Annex VI section 3, table 1
Index No	Chemical name	EC No	CAS No	Classification		Labelling			Specific Conc. Limits, M-factors and ATEs	Notes
Index No	Chemical name	EC No	CAS No	Hazard Class and Category Code(s)	Hazard statement Code(s)	Pictogram, Signal Word Code(s)	Hazard statement Code(s)	Suppl. Hazard statement Code(s)	Specific Conc. Limits, M-factors and ATEs	Notes
612-099-00-3	4-methyl-m-phenylenediamine; 2,4-toluenediamine	202-453-1	95-80-7	Carc. 1B Muta. 2 Repr. 2 Acute Tox. 3 * Acute Tox. 4 * STOT RE 2 * Skin Sens. 1 Aquatic Chronic 2	H350 H341 H361f* H301 H312 H373 H317 H411	GHS06 GHS08 GHS09 Dgr	H350 H341 H361f* H301 H312 H373 H317 H411

CLP Annex VI section 3, table 2, Index No 612-099-00-3

Last changed in the version in force 1 December 2010, by Regulation (EC) No 790/2009, the act that change names · Annex VI on this site

Annex VI section 3, table 2
Index No	International Chemical Identification	EC No	CAS No	Classification	Labelling	Concentration Limits	Notes
612-099-00-3	4-methyl-m-phenylenediamine; 2,4-toluenediamine	202-453-1	95-80-7	Carc. Cat. 2; R45 Muta. Cat. 3; R68 Repr. Cat. 3; R62 T; R25 Xn; R21-48/22 R43 N; R51-53	T; N R: 45-21-25-43-48/22-62-68-51/53 S: 53-45-61		E

Cosmetics Regulation Annex II, Reference number 364

No change to this entry since the first version the record holds, in force 11 July 2013. · Annex II on this site

Annex II, table 1
Reference number	Substance identification
Reference number	Chemical name/INN	CAS number	EC number
a	b	c	d
364	4-Methyl-m-phenylenediamine (Toluene-2,4-diamine) and its salts	95-80-7	202-453-1

REACH Annex XVII appendix 2, Index No 612-099-00-3

Last changed in the version in force 18 February 2012, by Regulation (EU) No 125/2012 and 2 others, the acts that change names · Annex XVII on this site

Annex XVII appendix 2, table 1
Substances	Index No	EC No	CAS No	Notes
4-Methyl-m-phenylenediamine; 2,4-Toluenediamine	612-099-00-3	202-453-1	95-80-7

REACH Annex XVII appendix 8, No 19

No change to this entry since the first version the record holds, in force 12 October 2008. · Annex XVII on this site

Annex XVII appendix 8, table 1
	CAS No	Index No	EC No	Substances
19.	95-80-7	612-099-00-3	202-453-1	4-methyl-m-phenylenediamine

REACH Annex XVII appendix 13, CAS No 95-80-7

Last changed in the version in force 4 January 2021, by Regulation (EU) 2020/2081 and 3 others, the acts that change names · Annex XVII on this site

Annex XVII appendix 13, table 1
Substance name	EC No	CAS No	Concentration limit (by weight)
4-methyl-m- phenylenediamine	202-453-1	95-80-7	0,0005 %

Look up a number

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Its history

4 January 2021 · added · REACH Annex XVII appendix 13, CAS No 95-80-7

Recorded in the version in force 4 January 2021, by Regulation (EU) 2020/2081 and 3 others, the acts that change names. The change on its version page

Added entries, Annex XVII appendix 13, table 1
Identifiers	Substance name	EC No	CAS No	Concentration limit (by weight)
CAS No 95-80-7CAS 95-80-7EC 202-453-1	4-methyl-m- phenylenediamine	202-453-1	95-80-7	0,0005 %

18 February 2012 · amended · REACH Annex XVII appendix 2, Index No 612-099-00-3

Recorded in the version in force 18 February 2012, by Regulation (EU) No 125/2012 and 2 others, the acts that change names. The change on its version page

Amended entries, Annex XVII appendix 2, table 1
Identifiers	Version	Substances	Index No	EC No	CAS No	Notes
Index No 612-099-00-3CAS 95-80-7EC 202-453-1	Before	~~4-Methyl-m-phenylenediamine~~	612-099-00-3	202-453-1	95-80-7
Index No 612-099-00-3CAS 95-80-7EC 202-453-1	After	4-Methyl-m-phenylenediamine; 2,4-Toluenediamine	612-099-00-3	202-453-1	95-80-7

18 February 2012 · amended · REACH Annex XVII appendix 2, Index No 612-151-00-5

Recorded in the version in force 18 February 2012, by Regulation (EU) No 125/2012 and 2 others, the acts that change names. The change on its version page

Amended entries, Annex XVII appendix 2, table 1
Identifiers	Version	Substances	Index No	EC No	CAS No	Notes
Index No 612-151-00-5CAS 25376-45-8CAS 823-40-5CAS 95-80-7EC 202-453-1EC 212-513-9EC 246-910-3	Before	~~Diaminotoluene, technical~~ product ~~— mixture~~ of ~~[2] and [3] methyl-phenylenediamine [1]~~ 4-methyl-m-phenylene diamine ~~[2]~~ 2-methyl-m-phenylene diamine ~~[3]~~	612-151-00-5	~~246-910-3[1] 202-453-1 [2] 212-513-9 [3]~~	~~25376-45-8 [1] 95-80-7 [2] 823-40-5 [3]~~	E
	After	Methyl-phenylene diamine; Diaminotoluene; [technical product – reaction mass of 4-methyl-m-phenylene diamine (EC No 202-453-1) and 2-methyl-m-phenylene diamine (EC No 212-513-9)]	612-151-00-5	—	—

1 December 2010 · amended · CLP Annex VI section 3, Index No 612-099-00-3

Recorded in the version in force 1 December 2010, by Regulation (EC) No 790/2009, the act that change names. The change on its version page

Amended entries, Annex VI section 3, table 1
Identifiers	Version	Index No	International Chemical Identification	EC No	CAS No	Classification		Labelling
Identifiers	Version	Index No	International Chemical Identification	EC No	CAS No	Hazard Class and Category Code(s)	Hazard statement Code(s)	Pictogram, Signal Word Code(s)	Hazard statement Code(s)	Suppl. Hazard statement Code(s)
Index No 612-099-00-3CAS 95-80-7EC 202-453-1	Before	612-099-00-3	4-methyl-m-phenylenediamine; 2,4-toluenediamine	202-453-1	95-80-7	Carc. 1B Acute Tox. 3 * Acute Tox. 4 * ~~Eye Irrit.~~ 2 Skin Sens. 1 Aquatic Chronic 2	H350 H301 H312 ~~H319~~ H317 H411	GHS06 GHS08 GHS09 Dgr	H350 H301 H312 ~~H319~~ H317 H411
Index No 612-099-00-3CAS 95-80-7EC 202-453-1	After	612-099-00-3	4-methyl-m-phenylenediamine; 2,4-toluenediamine	202-453-1	95-80-7	Carc. 1B Muta. 2 Repr. 2 Acute Tox. 3 * Acute Tox. 4 * STOT RE 2 * Skin Sens. 1 Aquatic Chronic 2	H350 H341 H361f* H301 H312 H373 H317 H411	GHS06 GHS08 GHS09 Dgr	H350 H341 H361f* H301 H312 H373 H317 H411

1 December 2010 · amended · CLP Annex VI section 3, Index No 612-151-00-5

Recorded in the version in force 1 December 2010, by Regulation (EC) No 790/2009, the act that change names. The change on its version page

Amended entries, Annex VI section 3, table 1
Identifiers	Version	Index No	International Chemical Identification	EC No	CAS No	Classification		Labelling
Identifiers	Version	Index No	International Chemical Identification	EC No	CAS No	Hazard Class and Category Code(s)	Hazard statement Code(s)	Pictogram, Signal Word Code(s)	Hazard statement Code(s)	Suppl. Hazard statement Code(s)
Index No 612-151-00-5CAS 25376-45-8CAS 823-40-5CAS 95-80-7EC 202-453-1EC 212-513-9EC 246-910-3	Before	612-151-00-5	~~diaminotoluene, technical~~ product - reaction mass of ~~[2]~~ and ~~[3]; methyl-phenylenediamine; [1] 4-methyl-m-phenylene diamine; [2]~~ 2-methyl-m-phenylene diamine ~~[3]~~	~~246-910-3 [1] 202-453-1 [2] 212-513-9 [3]~~	~~25376-45-8 [1] 95-80-7 [2] 823-40-5 [3]~~	Carc. 1B Acute Tox. 3 * Acute Tox. 4 * ~~Acute Tox. 4~~ * Eye Irrit. 2 Skin Sens. 1 Aquatic Chronic 2	H350 H301 ~~H332~~ H312 H319 H317 H411	GHS06 GHS08 GHS09 Dgr	H350 H301 ~~H332~~ H312 H319 H317 H411
	After	612-151-00-5	methyl-phenylene diamine; diaminotoluene; [technical product – reaction mass of 4-methyl-m-phenylene diamine (EC No 202-453-1) and 2-methyl-m-phenylene diamine (EC No 212-513-9)]	—	—	Carc. 1B Muta. 2 Repr. 2 Acute Tox. 3 * Acute Tox. 4 * STOT RE 2 * Eye Irrit. 2 Skin Sens. 1 Aquatic Chronic 2	H350 H341 H361f* H301 H312 H373 H319 H317 H411	GHS06 GHS08 GHS09 Dgr	H350 H341 H361f* H301 H312 H373 H319 H317 H411

1 December 2010 · amended · CLP Annex VI section 3, table 2, Index No 612-099-00-3

Recorded in the version in force 1 December 2010, by Regulation (EC) No 790/2009, the act that change names. The change on its version page

Amended entries, Annex VI section 3, table 2
Identifiers	Version	Index No	International Chemical Identification	EC No	CAS No	Classification	Labelling	Concentration Limits	Notes
Index No 612-099-00-3CAS 95-80-7EC 202-453-1	Before	612-099-00-3	4-methyl-m-phenylenediamine; 2,4-toluenediamine	202-453-1	95-80-7	Carc. Cat. 2; R45 T; R25 Xn; ~~R21 Xi; R36~~ R43 N; R51-53	T; N R: ~~45-21-25-36-43-51/53~~ S: 53-45-61		E
Index No 612-099-00-3CAS 95-80-7EC 202-453-1	After	612-099-00-3	4-methyl-m-phenylenediamine; 2,4-toluenediamine	202-453-1	95-80-7	Carc. Cat. 2; R45 Muta. Cat. 3; R68 Repr. Cat. 3; R62 T; R25 Xn; R21-48/22 R43 N; R51-53	T; N R: 45-21-25-43-48/22-62-68-51/53 S: 53-45-61		E

1 December 2010 · amended · CLP Annex VI section 3, table 2, Index No 612-151-00-5

Recorded in the version in force 1 December 2010, by Regulation (EC) No 790/2009, the act that change names. The change on its version page

Amended entries, Annex VI section 3, table 2
Identifiers	Version	Index No	International Chemical Identification	EC No	CAS No	Classification	Labelling	Concentration Limits	Notes
Index No 612-151-00-5CAS 25376-45-8CAS 823-40-5CAS 95-80-7EC 202-453-1EC 212-513-9EC 246-910-3	Before	612-151-00-5	~~diaminotoluene, technical~~ product - reaction mass of ~~[2]~~ and ~~[3]; methyl-phenylenediamine; [1] 4-methyl-m-phenylene diamine; [2]~~ 2-methyl-m-phenylene diamine ~~[3]~~	~~246-910-3 [1] 202-453-1 [2] 212-513-9 [3]~~	~~25376-45-8 [1] 95-80-7 [2] 823-40-5 [3]~~	Carc. Cat. 2; R45 T; R25 Xn; ~~R20/21~~ Xi; R36 R43 N; R51-53	T; N R: ~~45-20/21-25-36-43-51/53~~ S: 53-45-61		E
	After	612-151-00-5	methyl-phenylene diamine; diaminotoluene; [technical product – reaction mass of 4-methyl-m-phenylene diamine (EC No 202-453-1) and 2-methyl-m-phenylene diamine (EC No 212-513-9)]	—	—	Carc. Cat. 2; R45 Muta. Cat. 3; R68 Repr. Cat. 3; R62 T; R25 Xn; R21-48/22 Xi; R36 R43 N; R51-53	T; N R: 45-21-25-36-43-48/22-62-68-51/53 S: 53-45-61		E

Sources

CLP: every version the record holds; rows read from EUR-Lex consolidated version 02008R1272-20270101, in force 1 January 2027 (external, EUR-Lex)
Cosmetics Regulation: every version the record holds; rows read from EUR-Lex consolidated version 02009R1223-20260518, in force 18 May 2026 (external, EUR-Lex)
REACH: every version the record holds; rows read from EUR-Lex consolidated version 02006R1907-20260622, detected 11 September 2026 (external, EUR-Lex)

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