CAS number

CAS 108-46-3 resorcinol

CAS 108-46-3 · EC 203-585-2 · Index No 604-010-00-1

Where CAS 108-46-3 appears: every table entry that prints it among its identifiers, in the newest version of each act this record holds, and every recorded change to those entries. Many entries name a group of substances and print no number, so absence here is not absence from the law. Not legal advice.

Where it appears now

CLP Annex VI section 3, Index No 604-010-00-1

Last changed in the version in force 1 September 2025, by Regulation (EU) 2024/197, the act that change names · Annex VI on this site

Annex VI section 3, table 1
Index No	Chemical name	EC No	CAS No	Classification		Labelling			Specific Conc. Limits, M-factors and ATEs	Notes
Index No	Chemical name	EC No	CAS No	Hazard Class and Category Code(s)	Hazard statement Code(s)	Pictogram, Signal Word Code(s)	Hazard statement Code(s)	Suppl. Hazard statement Code(s)	Specific Conc. Limits, M-factors and ATEs	Notes
604-010-00-1	resorcinol; 1,3-benzenediol	203-585-2	108-46-3	Acute Tox. 4 STOT SE 1 Skin Irrit. 2 Eye Irrit. 2 Skin Sens. 1B Aquatic Acute 1	H302 H370 (nervous system) H315 H319 H317 H400	GHS07 GHS08 GHS09 Dgr	H302 H370 (nervous system) H315 H319 H317 H400		oral: ATE = 500 mg/kg bw M = 1

CLP Annex VI section 3, table 2, Index No 604-010-00-1

No change to this entry since the first version the record holds, in force 1 December 2010. · Annex VI on this site

Annex VI section 3, table 2
Index No	International Chemical Identification	EC No	CAS No	Classification	Labelling	Concentration Limits	Notes
604-010-00-1	resorcinol; 1,3-benzenediol	203-585-2	108-46-3	Xn; R22 Xi; R36/38 N; R50	Xn; N R: 22-36/38-50 S: (2-)26-61	Xn; R22: C ≥ 10 %

Cosmetics Regulation Annex III, Reference number 22

Last changed in the version in force 17 December 2022, by Regulation (EU) 2022/1531 and Regulation (EU) 2022/2195, the acts that change names · Annex III on this site

Annex III, table 1
Reference number	Substance identification				Restrictions			Wording of conditions of use and warnings
Reference number	Chemical name/INN	Name of Common Ingredients Glossary	CAS number	EC number	Product type, body parts	Maximum concentration in ready for use preparation	Other	Wording of conditions of use and warnings
a	b	c	d	e	f	g	h	i
22	1,3-benzenediol	Resorcinol	108-46-3	203-585-2	(a) Hair dye substance in oxidative hair dye products		For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1,25 %	(a) To be printed on the label: The mixing ratio. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains resorcinol. Rinse hair well after application. Rinse eyes immediately if product comes into contact with them. Do not use to dye eyelashes.
					(b) Products intended for colouring eyelashes		(b) For professional use only.	(b) To be printed on the label: The mixing ratio. For professional use only. Contains resorcinol. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: has a rash on the face or sensitive, irritated and damaged scalp, has experienced any reaction after colouring hair or eyelashes, has experienced a reaction to a temporary black henna tattoo in the past. Rinse eyes immediately if product comes into contact with them.
					(c) Hair lotions and shampoos	(c) 0,5 %		(c) Contains resorcinol.

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Its history

1 September 2025 · amended · CLP Annex VI section 3, Index No 604-010-00-1

Recorded in the version in force 1 September 2025, by Regulation (EU) 2024/197, the act that change names. The change on its version page

Amended entries, Annex VI section 3, table 1
Identifiers	Version	Index No	Chemical name	EC No	CAS No	Classification		Labelling			Specific Conc. Limits, M-factors and ATEs	Notes
Identifiers	Version	Index No	Chemical name	EC No	CAS No	Hazard Class and Category Code(s)	Hazard statement Code(s)	Pictogram, Signal Word Code(s)	Hazard statement Code(s)	Suppl. Hazard statement Code(s)	Specific Conc. Limits, M-factors and ATEs	Notes
Index No 604-010-00-1CAS 108-46-3EC 203-585-2	Before	604-010-00-1	resorcinol; 1,3-benzenediol	203-585-2	108-46-3	Acute Tox. 4 * Eye Irrit. 2 Skin ~~Irrit. 2~~ Aquatic Acute 1	H302 H319 ~~H315~~ H400	GHS07 GHS09 ~~Wng~~	H302 H319 ~~H315~~ H400		*
Index No 604-010-00-1CAS 108-46-3EC 203-585-2	After	604-010-00-1	resorcinol; 1,3-benzenediol	203-585-2	108-46-3	Acute Tox. 4 STOT SE 1 Skin Irrit. 2 Eye Irrit. 2 Skin Sens. 1B Aquatic Acute 1	H302 H370 (nervous system) H315 H319 H317 H400	GHS07 GHS08 GHS09 Dgr	H302 H370 (nervous system) H315 H319 H317 H400		oral: ATE = 500 mg/kg bw M = 1

17 December 2022 · amended · Cosmetics Regulation Annex III, Reference number 22

Recorded in the version in force 17 December 2022, by Regulation (EU) 2022/1531 and Regulation (EU) 2022/2195, the acts that change names. The change on its version page

Amended entries, Annex III, table 1
Identifiers	Version	Reference number	Substance identification				Restrictions			Wording of conditions of use and warnings
		Reference number	Chemical name/INN	Name of Common Ingredients Glossary	CAS number	EC number	Product type, body parts	Maximum concentration in ready for use preparation	Other	Wording of conditions of use and warnings
		a	b	c	d	e	f	g	h	i
Reference number 22CAS 108-46-3EC 203-585-2	Before	22	1,3-benzenediol	Resorcinol	108-46-3	203-585-2	(a) Hair dye substance in oxidative hair dye products		For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1,25 %	(a) To be printed on the label: The mixing ratio. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains resorcinol. Rinse hair well after application. Rinse eyes immediately if product comes into contact with them. Do not use to dye ~~eyelashes or eyebrows.~~
							(b) Products intended for colouring eyelashes		(b) For professional use only.	(b) To be printed on the label: The mixing ratio. For professional use only. Contains resorcinol. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: has a rash on the face or sensitive, irritated and damaged scalp, has experienced any reaction after colouring hair or eyelashes, has experienced a reaction to a temporary black henna tattoo in the past. Rinse eyes immediately if product comes into contact with them.
							(c) Hair lotions and shampoos	(c) 0,5 %		(c) Contains resorcinol.
	After	22	1,3-benzenediol	Resorcinol	108-46-3	203-585-2	(a) Hair dye substance in oxidative hair dye products		For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1,25 %	(a) To be printed on the label: The mixing ratio. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains resorcinol. Rinse hair well after application. Rinse eyes immediately if product comes into contact with them. Do not use to dye eyelashes.
							(b) Products intended for colouring eyelashes		(b) For professional use only.	(b) To be printed on the label: The mixing ratio. For professional use only. Contains resorcinol. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: has a rash on the face or sensitive, irritated and damaged scalp, has experienced any reaction after colouring hair or eyelashes, has experienced a reaction to a temporary black henna tattoo in the past. Rinse eyes immediately if product comes into contact with them.
							(c) Hair lotions and shampoos	(c) 0,5 %		(c) Contains resorcinol.

30 April 2014 · amended · Cosmetics Regulation Annex III, Reference number 22

Recorded in the version in force 30 April 2014, by Regulation (EU) No 358/2014, the act that change names. The change on its version page

Amended entries, Annex III, table 1
Identifiers	Version	Reference number	Substance identification				Restrictions			Wording of conditions of use and warnings
		Reference number	Chemical name/INN	Name of Common Ingredients Glossary	CAS number	EC number	Product type, body parts	Maximum concentration in ready for use preparation	Other	Wording of conditions of use and warnings
		a	b	c	d	e	f	g	h	i
Reference number 22CAS 108-46-3EC 203-585-2	Before	22	1,3-benzenediol	Resorcinol	108-46-3	203-585-2	(a) Hair dye substance in oxidative hair dye products		For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1,25 %	(a) 1. To be printed on the label: The mixing ratio. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. ~~temporary~~ black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains resorcinol. Rinse hair well after application. Rinse eyes immediately if product comes into contact with them. Do not use to dye eyelashes or eyebrows. 2. To be printed on the label: The mixing ratio. For professional use only. Contains resorcinol. Rinse eyes immediately if product comes into contact with them. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. (b) Contains resorcinol.
							(b) Products intended for colouring eyelashes		(b) For professional use only.
							(c) Hair lotions and shampoos	(c) 0,5 %
	After	22	1,3-benzenediol	Resorcinol	108-46-3	203-585-2	(a) Hair dye substance in oxidative hair dye products		For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1,25 %	(a) To be printed on the label: The mixing ratio. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains resorcinol. Rinse hair well after application. Rinse eyes immediately if product comes into contact with them. Do not use to dye eyelashes or eyebrows.
							(b) Products intended for colouring eyelashes		(b) For professional use only.	(b) To be printed on the label: The mixing ratio. For professional use only. Contains resorcinol. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: has a rash on the face or sensitive, irritated and damaged scalp, has experienced any reaction after colouring hair or eyelashes, has experienced a reaction to a temporary black henna tattoo in the past. Rinse eyes immediately if product comes into contact with them.
							(c) Hair lotions and shampoos	(c) 0,5 %		(c) Contains resorcinol.

1 April 2014 · amended · Cosmetics Regulation Annex III, Reference number 22

Recorded in the version in force 1 April 2014, by Regulation (EU) No 483/2013, the act that change names. The change on its version page

Amended entries, Annex III, table 1
Identifiers	Version	Reference number	Substance identification				Restrictions			Wording of conditions of use and warnings
		Reference number	Chemical name/INN	Name of Common Ingredients Glossary	CAS number	EC number	Product type, body parts	Maximum concentration in ready for use preparation	Other	Wording of conditions of use and warnings
		a	b	c	d	e	f	g	h	i
Reference number 22CAS 108-46-3EC 203-585-2	Before	22	1,3-benzenediol	Resorcinol	108-46-3	203-585-2	(a) Hair dye substance in oxidative hair dye products		(a) ~~1. general use 2. professional use For 1~~ and 2: After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1,25 %	(a) 1. To be printed on the label: The mixing ratio. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains resorcinol. Rinse hair well after application. Rinse eyes immediately if product comes into contact with them. Do not use to dye eyelashes or eyebrows. 2. To be printed on the label: The mixing ratio. For professional use only. Contains resorcinol. Rinse eyes immediately if product comes into contact with them. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. (b) Contains resorcinol.
	Before	22	1,3-benzenediol	Resorcinol	108-46-3	203-585-2	(b) ~~Hair lotions and shampoos~~	~~(b) 0,5 %~~
	After	22	1,3-benzenediol	Resorcinol	108-46-3	203-585-2	(a) Hair dye substance in oxidative hair dye products		For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1,25 %	(a) 1. To be printed on the label: The mixing ratio. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. Contains resorcinol. Rinse hair well after application. Rinse eyes immediately if product comes into contact with them. Do not use to dye eyelashes or eyebrows. 2. To be printed on the label: The mixing ratio. For professional use only. Contains resorcinol. Rinse eyes immediately if product comes into contact with them. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. (b) Contains resorcinol.
							(b) Products intended for colouring eyelashes		(b) For professional use only.
							(c) Hair lotions and shampoos	(c) 0,5 %

31 July 2013 · amended · Cosmetics Regulation Annex III, Reference number 22

Recorded in the version in force 31 July 2013, by Regulation (EU) No 658/2013, the act that change names. The change on its version page

Amended entries, Annex III, table 1
Identifiers	Version	Reference number	Substance identification				Restrictions			Wording of conditions of use and warnings
		Reference number	Chemical name/INN	Name of Common Ingredients Glossary	CAS number	EC number	Product type, body parts	Maximum concentration in ready for use preparation	Other	Wording of conditions of use and warnings
		a	b	c	d	e	f	g	h	i
Reference number 22CAS 108-46-3EC 203-585-2	Before	22	~~Resorcinol~~	Resorcinol	108-46-3	203-585-2	(a) Hair dye substance in oxidative hair dye products		(a) 1. ~~General~~ use	(a) 1. To be printed on the label: The mixing ratio. ~~Contains resorcinol. Rinse hair well after application. Do not use to dye eyelashes or eyebrows. Rinse eyes immediately if product comes into contact with them.~~ Hair ~~colourants~~ can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. ~~Temporary~~ black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past.
							(a) Hair dye substance in oxidative hair dye products		2. ~~Professional~~ use For 1 and 2: After mixing under oxidative conditions the maximum concentration applied to hair must not exceed ~~2,5~~ % ~~calculated as free base~~	2. To be printed on the label: The mixing ratio. ~~For professional use only. Contains resorcinol. Rinse eyes immediately if product comes into contact with them.~~ Hair ~~colourants~~ can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. ~~Temporary~~ black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past.
							~~(b) Hair lotions and shampoos~~	~~(b) 0,5 %~~		~~(b) Contains resorcinol~~
	After	22	1,3-benzenediol	Resorcinol	108-46-3	203-585-2	(a) Hair dye substance in oxidative hair dye products		(a) 1. general use2. professional use For 1 and 2: After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1,25 %	(a) 1. To be printed on the label: The mixing ratio. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past.Contains resorcinol. Rinse hair well after application. Rinse eyes immediately if product comes into contact with them. Do not use to dye eyelashes or eyebrows. 2. To be printed on the label: The mixing ratio. For professional use only. Contains resorcinol. Rinse eyes immediately if product comes into contact with them. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past. (b) Contains resorcinol.
	After	22	1,3-benzenediol	Resorcinol	108-46-3	203-585-2	(b) Hair lotions and shampoos	(b) 0,5 %

11 July 2013 · amended · Cosmetics Regulation Annex III, Reference number 22

Recorded in the version in force 11 July 2013, by Regulation (EU) No 344/2013 and Regulation (EU) No 1197/2013, the acts that change names. The change on its version page

Amended entries, Annex III, table 1
Identifiers	Version	Reference number	Substance identification				Restrictions			Wording of conditions of use and warnings
		Reference number	Chemical name/INN	Name of Common Ingredients Glossary	CAS number	EC number	Product type, body parts	Maximum concentration in ready for use preparation	Other	Wording of conditions of use and warnings
		a	b	c	d	e	f	g	h	i
Reference number 22CAS 108-46-3EC 203-585-2	Before	22	Resorcinol	Resorcinol	108-46-3	203-585-2	(a) ~~Oxidising colouring agent for~~ hair ~~dyeing~~	~~5 %~~	General use ~~Not to be used on eyebrows~~	Contains ~~resorcinol~~ Rinse hair well after ~~application~~ Do not use to dye eyelashes or ~~eyebrows~~ Rinse eyes immediately if product comes into contact with ~~them~~
	Before	22	Resorcinol	Resorcinol	108-46-3	203-585-2	(a) ~~Oxidising colouring agent for~~ hair ~~dyeing~~	~~5 %~~	Professional use	For professional use ~~only~~ Contains ~~resorcinol~~ Rinse eyes immediately if product comes into contact with ~~them~~
	After	22	Resorcinol	Resorcinol	108-46-3	203-585-2	(a) Hair dye substance in oxidative hair dye products		(a) 1. General use	(a) 1. To be printed on the label: The mixing ratio. Contains resorcinol. Rinse hair well after application. Do not use to dye eyelashes or eyebrows. Rinse eyes immediately if product comes into contact with them. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past.
							(a) Hair dye substance in oxidative hair dye products		2. Professional useFor 1 and 2: After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,5 % calculated as free base	2. To be printed on the label: The mixing ratio. For professional use only. Contains resorcinol. Rinse eyes immediately if product comes into contact with them. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary black henna tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary black henna tattoo in the past.
							(b) Hair lotions and shampoos	(b) 0,5 %		(b) Contains resorcinol

Sources

CLP: every version the record holds; rows read from EUR-Lex consolidated version 02008R1272-20270101, in force 1 January 2027 (external, EUR-Lex)
Cosmetics Regulation: every version the record holds; rows read from EUR-Lex consolidated version 02009R1223-20260518, in force 18 May 2026 (external, EUR-Lex)

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