CAS number
CAS 103597-45-1 2,2'-methylenebis(6-(2H-benzotriazol-2-y…
CAS 103597-45-1 · EC 403-800-1 · Index No 604-052-00-0
Where CAS 103597-45-1 appears: every table entry that prints it among its identifiers, in the newest version of each act this record holds, and every recorded change to those entries. Many entries name a group of substances and print no number, so absence here is not absence from the law. Not legal advice.
Where it appears now
CLP Annex VI section 3, Index No 604-052-00-0
No change to this entry since the first version the record holds, in force 1 December 2010. · Annex VI on this site
| Index No | Chemical name | EC No | CAS No | Classification | Labelling | Specific Conc. Limits, M-factors and ATEs | Notes | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Hazard Class and Category Code(s) | Hazard statement Code(s) | Pictogram, Signal Word Code(s) | Hazard statement Code(s) | Suppl. Hazard statement Code(s) | ||||||
| 604-052-00-0 | 2,2'-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol) | 403-800-1 | 103597-45-1 | Aquatic Chronic 4 | H413 | — | H413 | |||
CLP Annex VI section 3, table 2, Index No 604-052-00-0
No change to this entry since the first version the record holds, in force 1 December 2010. · Annex VI on this site
| Index No | International Chemical Identification | EC No | CAS No | Classification | Labelling | Concentration Limits | Notes |
|---|---|---|---|---|---|---|---|
| 604-052-00-0 | 2,2'-methylenebis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol) | 403-800-1 | 103597-45-1 | R53 | R: 53 S: 61 |
Cosmetics Regulation Annex VI, Reference number 23
Last changed in the version in force , by Regulation (EU) 2018/885, the act that change names · Annex VI on this site
| Reference number | Substance identification | Conditions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|
| Chemical name/INN/XAN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, body parts | Maximum concentration in ready for use preparation | Other | ||
| a | b | c | d | e | f | g | h | i |
| 23 | 2,2′-Methylene- bis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)/Bisoctrizole | Methylene Bis-Benzotriazolyl Tetramethylbutylphenol | 103597-45-1 | 403-800-1 | 10 % | |||
Cosmetics Regulation Annex VI, Reference number 23a
Last changed in the version in force , by Regulation (EU) 2018/885, the act that change names · Annex VI on this site
| Reference number | Substance identification | Conditions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|
| Chemical name/INN/XAN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, body parts | Maximum concentration in ready for use preparation | Other | ||
| a | b | c | d | e | f | g | h | i |
| 23a | 2,2′-Methylene- bis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)/Bisoctrizole | Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (nano) | 103597-45-1 | 403-800-1 | 10 % | Not to be used in applications that may lead to exposure of the end user's lungs by inhalation. Only nanomaterials having the following characteristics are allowed: Purity ≥ 98,5 %, with 2,2′-methylene-bis-(6(2H-benzotriazol-2-yl)-4-(isooctyl)phenol) isomer fraction not exceeding 1,5 %; Solubility < 5 ng/L in water at 25 °C; Partition coefficient (Log Pow): 12,7 at 25 °C; Uncoated; Median particle size D50 (50 % of the number below this diameter): ≥ 120 nm of mass distribution and/or ≥ 60 nm of number size distribution. | ||
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Its history
· amended · Cosmetics Regulation Annex VI, Reference number 23
Recorded in the version in force , by Regulation (EU) 2018/885, the act that change names. The change on its version page
| Identifiers | Version | Reference number | Substance identification | Conditions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Chemical name/INN/XAN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, body parts | Maximum concentration in ready for use preparation | Other | ||||
| a | b | c | d | e | f | g | h | i | ||
| Reference number 23CAS 103597-45-1EC 403-800-1 | Before | 23 | Methylene Bis-Benzotriazolyl Tetramethylbutylphenol | 103597-45-1 | 403-800-1 | 10 % | ||||
| After | 23 | 2,2′-Methylene- bis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)/Bisoctrizole | Methylene Bis-Benzotriazolyl Tetramethylbutylphenol | 103597-45-1 | 403-800-1 | 10 % | ||||
· added · Cosmetics Regulation Annex VI, Reference number 23a
Recorded in the version in force , by Regulation (EU) 2018/885, the act that change names. The change on its version page
| Identifiers | Reference number | Substance identification | Conditions | Wording of conditions of use and warnings | |||||
|---|---|---|---|---|---|---|---|---|---|
| Chemical name/INN/XAN | Name of Common Ingredients Glossary | CAS number | EC number | Product type, body parts | Maximum concentration in ready for use preparation | Other | |||
| a | b | c | d | e | f | g | h | i | |
| Reference number 23aCAS 103597-45-1EC 403-800-1 | 23a | 2,2′-Methylene- bis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)/Bisoctrizole | Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (nano) | 103597-45-1 | 403-800-1 | 10 % | Not to be used in applications that may lead to exposure of the end user's lungs by inhalation. Only nanomaterials having the following characteristics are allowed: Purity ≥ 98,5 %, with 2,2′-methylene-bis-(6(2H-benzotriazol-2-yl)-4-(isooctyl)phenol) isomer fraction not exceeding 1,5 %; Solubility < 5 ng/L in water at 25 °C; Partition coefficient (Log Pow): 12,7 at 25 °C; Uncoated; Median particle size D50 (50 % of the number below this diameter): ≥ 120 nm of mass distribution and/or ≥ 60 nm of number size distribution. | ||
Sources
- CLP: every version the record holds; rows read from EUR-Lex consolidated version 02008R1272-20270101, in force 1 January 2027 (external, EUR-Lex)
- Cosmetics Regulation: every version the record holds; rows read from EUR-Lex consolidated version 02009R1223-20260518, in force 18 May 2026 (external, EUR-Lex)